Chitrakar Shasank, Aryal Saroj Babu, Shrestha Tirtha Man
Department of General Practice and Emergency Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
Department of Clinical Biochemistry, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2025 Mar;63(283):182-185. doi: 10.31729/jnma.8904. Epub 2025 Mar 31.
Pregnancy is the pro-thrombotic state. The objective of this report is to highlight the rare occurance of postpartum cavernous sinus thrombosis associated with eclampsia and gestational diabetes mellitus, emphasizing its clinical presentation. A 25-year-old Muslim female came with the complaint of headache,post auricular and right parietal region on 8th day post-partum. She had a history of postpartum eclampsia and Gestational Diabetes Mellitus for which she was treated with magnesium sulfate and oral hypoglycaemic agents respectively. MRV showed a filling defect in right transverse sinus, sigmoid sinus, and internal jugular vein. She was then admitted to the ward and was treated with heparin and antibiotics. She was then discharged on oral rivaroxaban. As pregnancy is itself a state of hyper-coagulable state, there seems to be a significant thrombosis risk. Hence clinicians should be aware of the possible thrombotic disorder in the background of this vignette.
妊娠是一种血栓前状态。本报告的目的是强调子痫和妊娠期糖尿病相关的产后海绵窦血栓形成的罕见情况,并着重介绍其临床表现。一名25岁的穆斯林女性在产后第8天因头痛、耳后及右侧顶叶区域疼痛前来就诊。她有产后子痫和妊娠期糖尿病病史,分别接受了硫酸镁和口服降糖药治疗。磁共振静脉血管造影(MRV)显示右侧横窦、乙状窦和颈内静脉有充盈缺损。随后她被收入病房,接受肝素和抗生素治疗。之后她口服利伐沙班出院。由于妊娠本身就是一种高凝状态,似乎存在显著的血栓形成风险。因此,临床医生应了解在此病例背景下可能出现的血栓性疾病。