Bai Yiwei, Luo Xuan, Qian Wenwu, Geng Xuhui, Bi Xiaojing, Zhang Yunwei
College of Grassland Science and Technology, China Agricultural University, Beijing 100094, China.
J Agric Food Chem. 2025 Jul 23;73(29):18448-18455. doi: 10.1021/acs.jafc.5c05138. Epub 2025 Jul 14.
gene family is an important family of plant transcription factors, widely involved in various life activities. This study systematically identified the gene family in 76 barley genomes based on the barley pan-genome, revealing a total of 22,681 family members. Through orthologous gene group analysis, these genes were categorized into 383 orthologous gene groups (OGGs), with core and noncore genes identified. The results indicate that the gene family in barley cultivars and landraces exhibits greater genetic diversity compared to wild barley, while wild barley is enriched in noncore genes and subjected to stronger selective pressures. Furthermore, two significant genes, and , were uncovered through selective pressure analysis, with pan-genome analysis suggesting their important roles in barley reproduction. This is the first pan-genomic analysis of the gene family in barley, which reveals the evolutionary patterns and functional characteristics of the family in different barley categories. The findings provide new theoretical insights for the genetic improvement and precision breeding of barley.
基因家族是植物转录因子的一个重要家族，广泛参与各种生命活动。本研究基于大麦泛基因组，在76个大麦基因组中系统鉴定了该基因家族，共发现22,681个家族成员。通过直系同源基因组分析，这些基因被分为383个直系同源基因组（OGGs），并鉴定出核心基因和非核心基因。结果表明，与野生大麦相比，大麦栽培品种和地方品种中的该基因家族表现出更大的遗传多样性，而野生大麦中非核心基因富集且受到更强的选择压力。此外，通过选择压力分析发现了两个重要的基因，即 和 ，泛基因组分析表明它们在大麦繁殖中发挥重要作用。这是首次对大麦中该基因家族进行泛基因组分析，揭示了该家族在不同大麦类别中的进化模式和功能特征。这些发现为大麦的遗传改良和精准育种提供了新的理论见解。
