Shamma S A, Symmes D
Hear Res. 1985;19(1):1-13. doi: 10.1016/0378-5955(85)90094-2.
Two-tone interactions are recorded in the responses of single units in the superior temporal gyrus to contralateral acoustic stimulation of the awake squirrel monkey. Four response types are distinguished based primarily on the nature of the inhibitory responses elicited by two-tone stimuli, and secondarily on such criteria as the patterns of response to single tones and noise stimuli, thresholds, and spontaneous activity levels. Type A units display strong lateral inhibitory influences which may extend up to 2 octaves on either side, or both sides, of the BF. They are sharply tuned at all intensities and exhibit sustained response to single tone stimuli at the BF. The units have nonmonotonic rate-level functions, and show little or no response to broad band noise. Type A units have low spontaneous rates (less than 3 spikes/s) and relatively high thresholds (greater than or equal to 30 dB SPL). Type B units are characterized by relatively high spontaneous rates of activity (greater than 20 spikes/s) and inhibitory responses to single tone stimuli. Broad band noise may evoke strong excitatory response. Type C units summate the responses to the two-tone stimulus, and show little or no inhibitory influences. They have V-shaped tuning curves, monotonic rate-level functions, low thresholds (greater than or equal to 30 dB SPL), moderate spontaneous rates (ca. 10 spikes/s), and a strong and sustained response to noise and single tone stimuli. Type D units show 'temporal inhibition' to two-tone stimuli, in that an excitatory response to the first tone suppresses (adapts or inhibits) the response to the second tone. These units generally have moderate to broad frequency tuning and phasic responses to single tone stimuli. Histological examination of electrode tracks suggests that Type A units are restricted to A1 (and possibly the rostral field) while other types are distributed over all auditory fields.
在清醒松鼠猴的颞上回中，对单神经元对侧听觉刺激的反应进行了双音相互作用的记录。主要根据双音刺激引发的抑制反应的性质，其次根据对单音和噪声刺激的反应模式、阈值和自发活动水平等标准，区分出四种反应类型。A型神经元表现出强烈的侧向抑制作用，这种抑制作用可能在BF两侧或一侧向上延伸多达2个八度。它们在所有强度下都有尖锐的调谐，并且对BF处的单音刺激表现出持续反应。这些神经元具有非单调的速率-强度函数，对宽带噪声几乎没有反应或无反应。A型神经元的自发发放率较低（小于3个脉冲/秒），阈值相对较高（大于或等于30 dB SPL）。B型神经元的特征是相对较高的自发活动率（大于20个脉冲/秒）以及对单音刺激的抑制反应。宽带噪声可能引发强烈的兴奋反应。C型神经元对双音刺激的反应进行总和，几乎没有或没有抑制作用。它们具有V形调谐曲线、单调的速率-强度函数、低阈值（大于或等于30 dB SPL）、中等自发发放率（约10个脉冲/秒），并且对噪声和单音刺激有强烈且持续的反应。D型神经元对双音刺激表现出“时间抑制”，即对第一个音的兴奋反应会抑制（适应或抑制）对第二个音的反应。这些神经元通常具有中等至较宽的频率调谐，并且对单音刺激有相位反应。电极轨迹的组织学检查表明，A型神经元局限于A1（可能还有吻侧区），而其他类型分布在所有听觉区域。
