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[周围神经节段性血供对其轴突再生影响的实验研究]

[Experimental investigation of the effect of segmental blood supplies to peripheral nerves on their axonal regeneration].

作者信息

Kameda I

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1985 Jul;59(7):691-705.

PMID:4067370
Abstract

Experimental investigations, with median nerve of adult cat, of axonal regeneration in nerve graft, fresh and predegenerated, with or without segmental blood supply gave following results. Four different kinds of nerve graft were performed in 4 groups. In group A and B, fresh 3 cm nerve graft was placed with or without segmental blood supply, respectively, and in group C and D, predegenerated nerve graft was placed with or without segmental blood supply, respectively. Number of regenerated axons was more and its diameter was larger in group A, compared with group B, within 2 months postop., but those became nearly equal after 3 months postop. In group C, the number of axons remained more and its diameter larger than in group D until 3 months postop. Of 4 groups, regenerated axons outnumbered other groups in group C, but mean diameter of them was the largest in group A.

摘要

以成年猫的正中神经为实验对象,对带或不带节段性血供的新鲜及预先变性的神经移植体中的轴突再生进行了实验研究,结果如下。4组分别进行了4种不同类型的神经移植。A组和B组分别植入带或不带节段性血供的3厘米新鲜神经移植体,C组和D组分别植入带或不带节段性血供的预先变性神经移植体。术后2个月内,A组再生轴突的数量更多且直径更大,与B组相比,但术后3个月后两者几乎相等。在C组中,直到术后3个月,轴突数量仍比D组多且直径更大。在4组中,C组再生轴突数量超过其他组,但A组中再生轴突的平均直径最大。

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