Klein Marie, Zadnikar Marcel, Marti Lukas
Klinik für Chirurgie, Kantonsspital St. Gallen, Rorschacherstr. 95, 9007 St. Gallen, Schweiz.
Klinik für Chirurgie, Universitätsklinikum Mannheim, Mannheim, Deutschland.
Chirurgie (Heidelb). 2025 Sep;96(9):721-727. doi: 10.1007/s00104-025-02336-6. Epub 2025 Jul 18.
An anal fissure is a painful lesion of the anal canal. The acute form often heals spontaneously and should be treated conservatively. The treatment of chronic anal fissures is the subject of many studies but the treatment recommendations of international guidelines are contradictory. Conservative treatment consists of chemical sphincterotomy using sphincter-relaxing drugs, such as calcium channel antagonists, nitrates or botulinum toxin and leads to healing in only about 50% of patients with a prolonged healing time and a high rate of recurrence. In contrast surgical treatment is much more effective. Lateral internal sphincterotomy is the most effective treatment with a success rate of >90%. Fissurectomy with a success rate of 80% is preferred in German-speaking countries due to its much lower risk of incontinence.
肛裂是肛管的一种疼痛性病变。急性肛裂通常可自愈,应采用保守治疗。慢性肛裂的治疗是许多研究的主题,但国际指南的治疗建议相互矛盾。保守治疗包括使用括约肌松弛药物进行化学性括约肌切开术,如钙通道拮抗剂、硝酸盐或肉毒杆菌毒素,仅约50%的患者可愈合,愈合时间延长且复发率高。相比之下,手术治疗效果要好得多。侧方内括约肌切开术是最有效的治疗方法,成功率>90%。在德语国家,由于失禁风险低得多,成功率为80%的肛裂切除术更受青睐。