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资源有限地区一名年轻女孩的卵巢卵黄囊瘤:来自索马里的罕见病例报告

Ovarian Yolk Sac Tumor in a Young Girl in a Resource-Limited Setting: A Rare Case Report From Somalia.

作者信息

Hussein Safio Ahmed, Hussein Ahmed Issak, Omar Abdikarim Ali, Hirsi Mohamed Omar, Mohamed Najma Adan, Dalmar Abdirashid Abdullahi, Hirei Hanan Hassan, Iyow Sowdo Nur

机构信息

Obstetrics and Gynecology Department, Mogadishu Somalia Turkish Training and Research Hospital, Mogadishu, Somalia.

General Surgery department, Mogadishu Somalia Turkish Training and Research Hospital, Mogadishu, Somalia.

出版信息

Int Med Case Rep J. 2025 Jul 17;18:887-891. doi: 10.2147/IMCRJ.S518785. eCollection 2025.

Abstract

Ovarian yolk sac tumors, accounting for less than 1% of all malignant ovarian germ cell tumors, primarily affect adolescents and young women. These tumors are typically unilateral, making fertility preservation a critical consideration. Despite their rarity, they generally respond well to chemotherapy, leading to a favorable prognosis. This report describes a 21-year-old woman presenting with abdominal pain and distension. Imaging revealed a substantial pelvic mass, with alpha-fetoprotein (AFP) levels elevated to 2258 mg/mL. She underwent a left salpingo-oophorectomy, and histopathology confirmed the presence of an ovarian yolk sac tumor. Timely diagnosis and treatment play a crucial role in patient outcomes. This case underscores the diagnostic and therapeutic challenges in a resource-constrained setting with limited access to chemotherapy necessitating transfer of most patients to abroad for oncology centers, making difficult for follow up and surveillance of patients, highlighting the pivotal role of surgical management and ongoing monitoring.

摘要

卵巢卵黄囊瘤占所有恶性卵巢生殖细胞肿瘤的比例不到1%,主要影响青少年和年轻女性。这些肿瘤通常为单侧性,这使得保留生育功能成为一个关键考虑因素。尽管它们很罕见,但一般对化疗反应良好,预后较好。本报告描述了一名21岁女性,她出现腹痛和腹胀。影像学检查发现盆腔有一个较大的肿块,甲胎蛋白(AFP)水平升高至2258mg/mL。她接受了左侧输卵管卵巢切除术,组织病理学证实存在卵巢卵黄囊瘤。及时诊断和治疗对患者的预后起着至关重要的作用。该病例凸显了在资源有限、难以获得化疗的情况下所面临的诊断和治疗挑战,这使得大多数患者必须转到国外的肿瘤中心,给患者的随访和监测带来困难,突出了手术管理和持续监测的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a19d/12278962/52ee189c2333/IMCRJ-18-887-g0001.jpg

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