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刺胞动物出芽、增殖和组织再生的信号传导机制

Signaling Mechanism of Budding, Proliferation, and Tissue Regeneration in Cnidaria.

作者信息

Lv Jie, Chen Jinhong, Li Liangzhi, Geng Xiaoyu, Li Bingbing, Wang Mingke, Yang Jishun

机构信息

Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.

Naval Medical Center of PLA, Naval Medical University, Shanghai 200052, China.

出版信息

Curr Issues Mol Biol. 2025 Mar 24;47(4):219. doi: 10.3390/cimb47040219.

Abstract

Phylum Cnidaria occupies an early branching position in the evolution of eukaryotes, establishing both close and distant relationships with most other eukaryotic metazoans. Budding encompasses the complete processes of cell proliferation, differentiation, and tissue regeneration, making it an ideal model for exploring various aspects of cellular function and evolution. Additionally, budding serves as the primary reproductive method for increasing the cnidarian population. This asexual reproductive phase is critical for managing and mitigating cnidarian outbreaks. This paper summarizes the common factors influencing budding, the signaling pathways involved and their associated functions, and the methodologies employed in relevant research, providing a theoretical foundation for the prevention and control of cnidarian populations.

摘要

刺胞动物门在真核生物进化中占据早期分支位置,与大多数其他真核后生动物建立了密切和疏远的关系。出芽涵盖了细胞增殖、分化和组织再生的完整过程,使其成为探索细胞功能和进化各个方面的理想模型。此外,出芽是刺胞动物种群增加的主要繁殖方式。这个无性繁殖阶段对于管理和减轻刺胞动物爆发至关重要。本文总结了影响出芽的常见因素、涉及的信号通路及其相关功能,以及相关研究中采用的方法,为刺胞动物种群的预防和控制提供了理论基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1a/12025505/1672aa9e687e/cimb-47-00219-g001.jpg

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