131碘安替比林在人体皮下脂肪组织中的组织-血液分配系数的测定。
Determination of the tissue-to-blood partition coefficient for 131iodo-antipyrine in human subcutaneous adipose tissue.
作者信息
Jelnes R, Astrup A
出版信息
Scand J Clin Lab Invest. 1985 Oct;45(6):521-4. doi: 10.3109/00365518509155253.
131Iodo-antipyrine (131I-AP) is commonly used for blood flow measurements in adipose tissue. These estimations have been based on the assumption of the tissue-to-blood partition coefficient being 1 ml g-1. No exact determination of the tissue-to-blood partition coefficient for 131I-AP in adipose tissue has been carried out. In the present study a partition coefficient of 1.12 +/- 0.06 (mean +/- S.D.) for 131I-AP in adipose tissue has been determined based on the partition coefficient for 131I-AP between lipid-saline (1.24 ml g-1), red blood cells-plasma (0.64 ml g-1), protein-saline (0.19 ml g-1) and plasma-saline (0.84 ml ml-1).
131碘安替比林（131I-AP）常用于测量脂肪组织中的血流量。这些测量基于组织与血液的分配系数为1 ml g-1这一假设。目前尚未对131I-AP在脂肪组织中的组织与血液分配系数进行精确测定。在本研究中，基于131I-AP在脂质-盐水（1.24 ml g-1）、红细胞-血浆（0.64 ml g-1）、蛋白质-盐水（0.19 ml g-1）和血浆-盐水（0.84 ml ml-1）之间的分配系数，已测定出131I-AP在脂肪组织中的分配系数为1.12±0.06（平均值±标准差）。
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