Golman K, Almen T, Denneberg T, Nosslin B
Invest Radiol. 1977 Jul-Aug;12(4):353-6. doi: 10.1097/00004424-197707000-00009.
In nine subjects undergoing urography with metrizamide measurements of total serum clearance of 51Cr-EDTA have been made before, during, and after the urography. During the urography both total serum clearances and renal clearances were determined for 51Cr-EDTA and metrizamide. The present study in man confirms the previous results from investigations in rabbits, that most of the intravenously injected metrizamide is excreted through the kidneys, that tubular reabsorption of metrizamide occurs and suggests that metrizamide might be used with advantage for urography.
对9名接受泛影酰胺尿路造影的受试者，在造影前、造影期间和造影后进行了51Cr - EDTA总血清清除率的测定。在尿路造影期间，测定了51Cr - EDTA和泛影酰胺的总血清清除率及肾脏清除率。本项人体研究证实了先前在兔子身上的研究结果，即静脉注射的泛影酰胺大部分通过肾脏排泄，泛影酰胺存在肾小管重吸收，并提示泛影酰胺可有利地用于尿路造影。
