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妊娠期尿道平滑肌瘤:一例有症状盆腔肿物并成功手术治疗的罕见病例

Urethral Leiomyoma in Pregnancy: A Rare Case of Symptomatic Pelvic Mass With Successful Surgical Management.

作者信息

Latoui Rana Beloulou, Sulemana Abdul Samed, Chaudhry Minhal, Abbas Usama, Khan Muhammad Abdullah

机构信息

Obstetrics and Gynecology, Centre Hospitalo-Universitaire Ibn Rochd Hospital, Annaba, DZA.

Renal Medicine, Royal Devon University Hospital NHS Foundation Trust, Exeter, GBR.

出版信息

Cureus. 2025 Jun 25;17(6):e86720. doi: 10.7759/cureus.86720. eCollection 2025 Jun.

Abstract

Leiomyomas, benign tumors derived from smooth muscle, are typically found in the uterus. Urethral involvement is an exceptionally rare occurrence, particularly in the context of a pre-fashioned thigh flap. Our case, therefore, presents a unique and intriguing instance, with only a few similar cases reported. We present a case of a 27-year-old primigravida at 11 weeks gestation with a protruding anterior vaginal mass, pelvic heaviness, and recurrent urinary complaints. A well-circumscribed vascular mass came out through the vulval orifice on physical examination. Transvaginal ultrasonography and pelvic magnetic resonance imaging revealed a 6×4 cm-sized mass that originated from the anterior vaginal wall, and it did not invade the adjacent structures. The surgical resection through anterior vaginal route with the use of spinal anesthesia. Histopathological examination revealed urethral leiomyoma, and the diagnosis was supported by positive immunoreactivity for the smooth muscle markers. The recovery following surgery was uneventful, and the pregnancy was carried to term with a successful normal delivery, instilling hope and optimism in similar cases. Our case underscores the crucial role of obstetricians and gynecologists in considering urethral leiomyoma in the differential diagnosis of anterior vaginal wall masses, even in pregnancy. This emphasis on early multimodal treatment can significantly impact the outcome; good results can be achieved, and pregnancy outcomes can be improved with curative therapy.

摘要

平滑肌瘤是源自平滑肌的良性肿瘤,通常见于子宫。尿道受累极为罕见,尤其是在预制大腿皮瓣的情况下。因此,我们的病例呈现了一个独特且引人关注的实例,仅有少数类似病例报道。我们报告一例27岁初孕妇,孕11周,有阴道前壁肿物突出、盆腔坠胀及反复泌尿系统症状。体格检查发现一个边界清晰的血管性肿物经外阴口脱出。经阴道超声检查及盆腔磁共振成像显示一个6×4厘米大小的肿物,起源于阴道前壁,未侵犯相邻结构。采用脊髓麻醉经阴道前路进行手术切除。组织病理学检查显示为尿道平滑肌瘤,平滑肌标志物免疫反应阳性支持该诊断。术后恢复顺利,妊娠足月并成功顺产,为类似病例带来了希望和乐观情绪。我们的病例强调了妇产科医生在鉴别诊断阴道前壁肿物时考虑尿道平滑肌瘤的关键作用,即使在孕期也是如此。这种对早期多模式治疗的重视可显著影响治疗结果;通过根治性治疗可取得良好效果并改善妊娠结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f91/12291364/ec5ea8d70bfb/cureus-0017-00000086720-i01.jpg

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