Wang Ge, Ding Jin, Wu Hongguang, Chen Yanhong, Deng Xiaoqi, Li Hairui, Li Haiying
Department of Arrhythmia, Cardiovascular Medical Center, University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Department of Medicine, Shenzhen University, Shenzhen, China.
Front Cardiovasc Med. 2025 Jul 16;12:1552916. doi: 10.3389/fcvm.2025.1552916. eCollection 2025.
Primary cardiac tumors in the fetal and neonatal populations are rare. In neonates, these tumors may present with a range of clinical manifestations, from asymptomatic cases to severe arrhythmias, valvular obstruction, and cardiac dysfunction. This report describes a case of fatal malignant arrhythmia caused by a cardiac tumor in an 8-day-old neonate. The electrocardiogram at birth revealed multiple abnormalities, including ST-T segment alterations, intraventricular conduction block, and bundle branch block. By the sixth postnatal day, the patient developed rapid, polymorphic malignant ventricular arrhythmias. Despite aggressive treatment, the neonate ultimately suffered sudden cardiac death. This case underscores the potentially fatal risk of arrhythmias associated with cardiac tumors.
胎儿和新生儿群体中的原发性心脏肿瘤较为罕见。在新生儿中,这些肿瘤可能表现出一系列临床表现,从无症状病例到严重心律失常、瓣膜阻塞和心脏功能障碍。本报告描述了一例8天大新生儿因心脏肿瘤导致致命性恶性心律失常的病例。出生时的心电图显示出多种异常,包括ST-T段改变、室内传导阻滞和束支传导阻滞。出生后第6天,患者出现快速、多形性恶性室性心律失常。尽管进行了积极治疗,该新生儿最终仍发生心源性猝死。该病例强调了与心脏肿瘤相关的心律失常的潜在致命风险。