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腹腔镜子宫肌瘤切除术与妊娠结局:一项叙述性综述。

Laparoscopic Myomectomy and Pregnancy Outcomes: A Narrative Review.

作者信息

Sarli Vaia G, Vogiatzoglou Aikaterini Lydia, Charalampos Theofanakis, Sioutis Dimos, Panagopoulos Periklis, Machairiotis Nikolaos

机构信息

Third Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.

出版信息

Cureus. 2025 Jul 4;17(7):e87268. doi: 10.7759/cureus.87268. eCollection 2025 Jul.

Abstract

Uterine fibroids (leiomyomas) are common benign tumors in women of reproductive age and are often associated with infertility, heavy menstrual bleeding, and pelvic discomfort. Laparoscopic myomectomy (LSM) has emerged as a fertility-preserving alternative to open surgery, offering faster recovery and reduced perioperative morbidity. This review aims to evaluate the effectiveness of laparoscopic myomectomy in improving pregnancy outcomes among women with fibroid-related infertility. A literature review was conducted using PubMed and Web of Science to identify retrospective cohort studies, case reports, and systematic reviews assessing fertility outcomes after LSM. Data on patient demographics, fibroid characteristics, surgical technique, and reproductive outcomes were extracted and analyzed to assess trends in pregnancy rates, delivery methods, and complications. Fifteen retrospective cohort studies and one case report were included in the analysis. Postoperative pregnancy rates ranged from 44% to 62% across studies, with a high proportion of successful full-term deliveries. Vaginal delivery was feasible in many cases, and complications such as uterine rupture were rare (<1%). Proper suturing techniques and minimally invasive approaches contributed to favorable reproductive outcomes, with LSM proving to be effective even in cases of multiple or large fibroids. Laparoscopic myomectomy is a safe and effective surgical option for women seeking fertility preservation. The procedure is associated with high postoperative pregnancy and live birth rates, minimal complications, and promising obstetric outcomes. Continued advancements in laparoscopic techniques and further large-scale studies with long-term follow-up are needed to refine patient selection and optimize results.

摘要

子宫肌瘤是育龄期女性常见的良性肿瘤,常与不孕、月经过多和盆腔不适相关。腹腔镜子宫肌瘤切除术已成为一种保留生育功能的替代开放性手术的方法,具有恢复快和围手术期发病率低的优点。本综述旨在评估腹腔镜子宫肌瘤切除术对改善肌瘤相关性不孕女性妊娠结局的有效性。通过使用PubMed和Web of Science进行文献综述,以确定评估腹腔镜子宫肌瘤切除术后生育结局的回顾性队列研究、病例报告和系统评价。提取并分析了患者人口统计学、肌瘤特征、手术技术和生殖结局的数据,以评估妊娠率、分娩方式和并发症的趋势。分析纳入了15项回顾性队列研究和1例病例报告。各研究的术后妊娠率在44%至62%之间,足月分娩成功率较高。在许多情况下,阴道分娩是可行的,子宫破裂等并发症很少见(<1%)。适当的缝合技术和微创方法有助于获得良好的生殖结局,即使在肌瘤多发或肌瘤较大的情况下,腹腔镜子宫肌瘤切除术也被证明是有效的。对于寻求保留生育功能的女性,腹腔镜子宫肌瘤切除术是一种安全有效的手术选择。该手术与高术后妊娠率和活产率、极少的并发症以及良好的产科结局相关。需要腹腔镜技术的持续进步以及进一步的长期随访大规模研究,以优化患者选择并改善结果。

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本文引用的文献

1
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Pregnancy and delivery after laparoscopic myomectomy.腹腔镜子宫肌瘤切除术后的妊娠与分娩
J Minim Invasive Gynecol. 2005 May-Jun;12(3):241-6. doi: 10.1016/j.jmig.2005.03.011.
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Pregnancy outcomes and deliveries after laparoscopic myomectomy.
J Am Assoc Gynecol Laparosc. 2003 May;10(2):177-81. doi: 10.1016/s1074-3804(05)60295-2.

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