一名6岁自闭症谱系障碍男孩因高剂量重复经颅磁刺激引发过度大笑的病例报告。
A Case Report of High-Dose Repetitive Transcranial Magnetic Stimulation-Induced Excessive Laughing in a 6-Year-Old Boy With Autism Spectrum Disorder.
作者信息
Long Junzi, Liao Xingxing, Han Kaiyue, Chen Jiarou, Li Hui, Liu Ying, Tang Zhiqing, Zhang Hao
机构信息
School of Rehabilitation Capital Medical University Beijing China.
Beijing Bo'ai Hospital, China Rehabilitation Research Center Beijing China.
出版信息
Clin Case Rep. 2025 Jul 31;13(8):e70731. doi: 10.1002/ccr3.70731. eCollection 2025 Aug.
High-dose transcranial magnetic stimulation-induced excessive laughter in a 6-year-old autistic male. We hypothesized that this phenomenon reflected prefrontal disinhibition or exaggerated emotional response. This case emphasizes the necessity for modified treatment protocols with concurrent psychiatric assessment, emotional evaluation, and neurophysiological monitoring when encountering such adverse effects during neuromodulation therapy.
高剂量经颅磁刺激诱发一名6岁自闭症男性过度大笑。我们推测这种现象反映了前额叶抑制解除或情绪反应过度。该病例强调，在神经调节治疗期间遇到此类不良反应时，需要修订治疗方案，同时进行精神科评估、情绪评估和神经生理监测。
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