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多灶性内听道及颅内前庭神经鞘瘤:病例展示

Multifocal intravestibulocochlear and intracranial vestibular schwannomas: illustrative case.

作者信息

Foscolo Valentina, Salonna Francesco, Pontillo Vito, Messina Raffaella, Gennaro Luigi de, Signorelli Francesco, Quaranta Nicola A A

机构信息

Otolaryngology Unit, Department of Translational Biomedicine and Neurosciences (DiBraiN), University "Aldo Moro" of Bari, Puglia, Italy.

Division of Neurosurgery, Department of Translational Biomedicine and Neurosciences (DiBraiN), University "Aldo Moro" of Bari, Puglia, Italy.

出版信息

J Neurosurg Case Lessons. 2025 Aug 4;10(5). doi: 10.3171/CASE25116.

Abstract

BACKGROUND

Eighth cranial nerve schwannomas represent a rare pathological condition, and their sporadic unilateral multifocal presentation is even more uncommon. Here, the authors present a rare case of multifocal intravestibulocochlear and intracranial vestibular schwannomas (VSs) and review analogous cases in the existing literature.

OBSERVATIONS

A 54-year-old female patient presented to the authors' clinic in March 2024 with complaints of left-sided hearing loss, tinnitus, and vertigo. Gadolinium-enhanced MRI revealed a Koos grade III VS localized in the cerebellopontine angle (CPA) with extension in the internal auditory canal and a coexisting intravestibulocochlear schwannoma. CT imaging showed no cochlear fundus dilatation or bone erosion. The patient underwent a left transotic approach with blind sac closure of the external auditory canal. No continuity was observed between the inner ear and intrameatal-CPA VSs, confirming the presence of two distinct lesions.

LESSONS

This case emphasizes the importance of a preoperative radiological evaluation and the necessity of a multidisciplinary team to ensure optimal surgical treatment and complete tumor resection. https://thejns.org/doi/10.3171/CASE25116.

摘要

背景

第八颅神经鞘瘤是一种罕见的病理状况,其散发性单侧多灶性表现更为罕见。在此,作者报告一例罕见的多灶性内听道和颅内前庭神经鞘瘤(VS)病例,并回顾现有文献中的类似病例。

观察结果

一名54岁女性患者于2024年3月因左侧听力丧失、耳鸣和眩晕就诊于作者所在诊所。钆增强MRI显示一个Koos III级VS位于桥小脑角(CPA),延伸至内耳道,并存一个内听道神经鞘瘤。CT成像显示无蜗底扩张或骨质侵蚀。患者接受了左侧经耳道入路,外耳道盲袋封闭。未观察到内耳与内耳道- CPA VS之间存在连续性,证实存在两个不同的病变。

经验教训

该病例强调了术前影像学评估的重要性以及多学科团队确保最佳手术治疗和完整肿瘤切除的必要性。https://thejns.org/doi/10.3171/CASE25116

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbd0/12320726/e029dc2d18a5/CASE25116_figure_1.jpg

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