Tsuneda Masato, Abe Kota, Abe Yukinao, Ikeda Yohei, Kodate Asuka, Kanazawa Aki, Saito Makoto, Harada Rintaro, Watanabe Miho, Uno Takashi
Department of Radiation Oncology, MR Linac ART Division, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
Department of Radiology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan.
Tech Innov Patient Support Radiat Oncol. 2025 Jul 22;35:100323. doi: 10.1016/j.tipsro.2025.100323. eCollection 2025 Sep.
We developed and evaluated a multiplane cine magnetic resonance imaging (MRI) workflow for magnetic resonance (MR)-guided online adaptive radiation therapy (MRgOART) for gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Two patients underwent MRgOART using this workflow, which enabled real-time assessments of stomach motion and ensured accurate target coverage within a planning target volume. Our workflow allowed visualization of the stomach with complex intrafractional motion caused by respiration and peristalsis. The total treatment time was clinically acceptable. All fractions satisfied our dose constraints. Our workflow supports precise MRgOART delivery for targets with variable shapes and motion, such as gastric MALT lymphoma.
我们开发并评估了一种用于胃黏膜相关淋巴组织（MALT）淋巴瘤的磁共振（MR）引导在线自适应放射治疗（MRgOART）的多平面电影磁共振成像（MRI）工作流程。两名患者使用该工作流程接受了MRgOART，该流程能够实时评估胃部运动，并确保在计划靶区内准确覆盖靶区。我们的工作流程能够可视化因呼吸和蠕动导致的复杂分次内运动的胃部。总治疗时间在临床上是可接受的。所有分次均满足我们的剂量限制。我们的工作流程支持为形状和运动可变的靶区（如胃MALT淋巴瘤）精确实施MRgOART。
