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Microbial imprints on colorectal cancer: the epigenetic silencing of PHLPP1 as a prognostic nexus.

作者信息

Huang Xiangsheng, Bishehsari Faraz

机构信息

Gastroenterology Research Center (GRC), Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

MD Anderson Cancer Center-UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas, USA.

出版信息

BMJ Oncol. 2025 Jul 27;4(1):e000883. doi: 10.1136/bmjonc-2025-000883. eCollection 2025.

Abstract
摘要

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本文引用的文献

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Colorectal Cancer: Epidemiology, Risk Factors, and Public Health Strategies.
Digestion. 2025;106(2):91-99. doi: 10.1159/000543921. Epub 2025 Feb 12.
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Gut microbiota and epigenetics in colorectal cancer: implications for carcinogenesis and therapeutic intervention.
Epigenomics. 2024 Mar;16(6):403-418. doi: 10.2217/epi-2023-0382. Epub 2024 Feb 27.
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Potential Role of the Gut Microbiome In Colorectal Cancer Progression.
Front Immunol. 2022 Jan 7;12:807648. doi: 10.3389/fimmu.2021.807648. eCollection 2021.
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The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development.
Front Oncol. 2021 Apr 15;11:626349. doi: 10.3389/fonc.2021.626349. eCollection 2021.
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Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures.
Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24285-24295. doi: 10.1073/pnas.1912129116. Epub 2019 Nov 11.
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Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis.
Cell Mol Gastroenterol Hepatol. 2020;9(2):219-237. doi: 10.1016/j.jcmgh.2019.10.011. Epub 2019 Nov 2.
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Intestinal microbiota is altered in patients with colon cancer and modified by probiotic intervention.
BMJ Open Gastroenterol. 2017 Jul 3;4(1):e000145. doi: 10.1136/bmjgast-2017-000145. eCollection 2017.
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