Coelho Júnior Hélio José, Álvarez-Bustos Alejandro, Calvani Riccardo, Cacciatore Stefano, Picca Anna, Tosato Matteo, Landi Francesco, Marzetti Emanuele
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy; Biomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain; Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain.
Biomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain; Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain; Instituto de Investigación IdiPaz, Madrid, Spain.
J Frailty Aging. 2025 Aug;14(4):100062. doi: 10.1016/j.tjfa.2025.100062. Epub 2025 Aug 5.
The present study examined the associations between sarcopenia, operationalized through muscle strength or muscle power, and health parameters in Italian community-dwelling older adults.
Cross-sectional study.
Unconventional settings across Italy.
Italian older adults (65+ years) who provided a written informed consent.
Physical function was evaluated according to isometric handgrip strength (IHG) and 5-time sit-to-stand (5STS) performances. Muscle power parameters were estimated based on 5STS values. Sarcopenia was operationalized according to the presence of low physical function (i.e., IHG or 5STS), or low muscle power, plus low appendicular skeletal muscle mass. Health parameters included the capacity to perform the 400 m test, adherence to the Mediterranean (MED) diet, practice of physical activity (PA), blood pressure (BP) values, blood concentration of total cholesterol and glucose, verbal fluency, sleep quality, and self-reported health status.
Results indicated that sarcopenic indexes had a poor-to-moderate level of agreement. Moreover, results indicated that operationalizing sarcopenia using muscle power measures provided exclusive or stronger associations with health parameters. Specifically, older adults classified as sarcopenic based on muscle power values were less likely to complete the 400-meter walk test, more likely to engage in PA, reported poorer self-rated health, and showed lower adherence to the MED diet.
Findings of the present study indicated that sarcopenia indexes based on muscle strength or muscle power capture different aspects of older adults' health. Specifically, operationalizing sarcopenia using muscle power measures provided exclusive or stronger associations with health parameters.
本研究调查了意大利社区居住的老年人中，通过肌肉力量或肌肉功率来定义的肌肉减少症与健康参数之间的关联。
横断面研究。
意大利各地的非常规场所。
提供书面知情同意书的意大利老年人（65岁及以上）。
根据等长握力（IHG）和5次坐立试验（5STS）表现评估身体功能。基于5STS值估算肌肉功率参数。肌肉减少症根据低身体功能（即IHG或5STS）、或低肌肉功率、加上低四肢骨骼肌质量来定义。健康参数包括进行400米测试的能力、对地中海（MED）饮食的依从性、体育活动（PA）习惯、血压（BP）值、总胆固醇和血糖的血浓度、语言流畅性、睡眠质量以及自我报告的健康状况。
结果表明，肌肉减少症指标的一致性水平较差至中等。此外，结果表明，使用肌肉功率测量来定义肌肉减少症与健康参数有独特或更强的关联。具体而言，根据肌肉功率值被归类为肌肉减少症的老年人完成400米步行测试的可能性较小，进行体育活动的可能性较大，自我评定的健康状况较差，并且对地中海饮食的依从性较低。
本研究结果表明，基于肌肉力量或肌肉功率的肌肉减少症指标反映了老年人健康的不同方面。具体而言，使用肌肉功率测量来定义肌肉减少症与健康参数有独特或更强的关联。
