Kovacevic Natalija, Sirls Larry, Gilleran Jason, Peters Kenneth
William Beaumont Hospital, Corewell Health, Department of Urology, Royal Oak, MI, United States.
Front Urol. 2023 Dec 18;3:1323444. doi: 10.3389/fruro.2023.1323444. eCollection 2023.
Chronic pelvic pain conditions such as pudendal neuralgia pose significant treatment difficulty due to their elusive etiology and diverse symptomatology. Initially approved as a third or fourth-line treatment of non-obstructive urinary retention and fecal incontinence, neuromodulation has also proven effective for pelvic pain associated with urinary dysfunction. Recently, sacral and pudendal neuromodulation has demonstrated efficacy in managing a spectrum of chronic pelvic conditions including refractory pudendal neuralgia. The individualized approach of peripheral neuromodulation has opened new avenues for tailored medical interventions, extending its application to conditions such as pudendal neuralgia, post sling pain, and vulvodynia. New technologies leading to miniaturized neuromodulation devices such as Freedom stimulators (Curonix), allows us to implant leads and modulate nerves at precise pain targets. Further experience and research is needed to assess the impact of targeted neuromodulation on managing complex pelvic pain conditions.
诸如阴部神经痛之类的慢性盆腔疼痛病症,因其病因难以捉摸且症状多样,导致治疗难度极大。神经调节最初被批准用于治疗非梗阻性尿潴留和大便失禁的三线或四线治疗,现已证明对与排尿功能障碍相关的盆腔疼痛也有效。最近,骶神经和阴部神经调节已显示出在管理一系列慢性盆腔病症(包括难治性阴部神经痛)方面的疗效。外周神经调节的个体化方法为定制医疗干预开辟了新途径,将其应用扩展到阴部神经痛、吊带术后疼痛和外阴痛等病症。诸如Freedom刺激器(Curonix)等导致神经调节装置小型化的新技术,使我们能够在精确的疼痛靶点植入导线并调节神经。需要进一步的经验和研究来评估靶向神经调节对管理复杂盆腔疼痛病症的影响。