Zhang Huihui, Zhang Zhi, Zhu Jinjin, Du Changqing, Jin Hongfeng, Zhang Wenli, Liu Xiaowei, Zeng Wenping
Department of Cardiology, First People's Hospital of Linping District, Hangzhou, 311100, Zhejiang, P. R. China.
School of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, P. R. China.
Sci Rep. 2025 Aug 9;15(1):29204. doi: 10.1038/s41598-025-15136-z.
Hypertension is a significant public health concern, especially among younger adults. Effective management of risk factors and adherence to recommended lifestyle changes are crucial for preventing long-term cardiovascular complications. This study analyzed data from 11,514 hypertensive participants aged 18 to 65 from the NHANES 1999-2018. Risk factor targets included BMI, LDL-C, waist circumference, and HbA1c, while lifestyle goals focused on smoking cessation, alcohol consumption, physical activity, sodium, and fiber intake. Statistical analyses involved chi-square tests, t-tests, and multivariate logistic regression. The mean age was 50.66 years, with 50.94% being male. Only 15.62% of participants met the BMI target, 66.02% met the LDL-C target, and 29.19% achieved the waist circumference goal. Regarding lifestyle, 71.32% met the smoking cessation target, but only 23.45% met the physical activity goal, and 14.44% achieved sufficient fiber intake. Overall, just 2.41% of participants met all risk factor targets, and 0.03% met all lifestyle goals. Poorer outcomes were linked to lower socioeconomic status, lower education levels, and the presence of comorbidities. These findings highlight significant gaps in risk factor control and lifestyle adherence among non-elderly hypertensive patients, underscoring the need for tailored interventions to improve cardiovascular outcomes.
高血压是一个重大的公共卫生问题,在年轻成年人中尤为突出。有效管理风险因素并坚持推荐的生活方式改变对于预防长期心血管并发症至关重要。本研究分析了1999 - 2018年美国国家健康与营养检查调查(NHANES)中11514名年龄在18至65岁之间的高血压参与者的数据。风险因素目标包括体重指数(BMI)、低密度脂蛋白胆固醇(LDL-C)、腰围和糖化血红蛋白(HbA1c),而生活方式目标则侧重于戒烟、饮酒、身体活动、钠和纤维摄入量。统计分析包括卡方检验、t检验和多变量逻辑回归。平均年龄为50.66岁,男性占50.94%。只有15.62%的参与者达到了BMI目标,66.02%达到了LDL-C目标,29.19%实现了腰围目标。在生活方式方面,71.32%的参与者达到了戒烟目标,但只有23.45%达到了身体活动目标,14.44%实现了足够的纤维摄入量。总体而言,只有2.41%的参与者达到了所有风险因素目标,0.03%达到了所有生活方式目标。较差的结果与较低的社会经济地位、较低的教育水平和合并症的存在有关。这些发现凸显了非老年高血压患者在风险因素控制和生活方式坚持方面存在的显著差距,强调了需要采取针对性干预措施来改善心血管结局。