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乳腺癌放疗女性随时间推移产生痛苦的相关因素:一项评估数字信息工具的试点研究的见解

Factors associated with distress over time in women with breast cancer undergoing radiotherapy: insights from a pilot study assessing a digital information tool.

作者信息

Grynne Annika, Fristedt Sofi, Wiklund Désirée Bourghardt, Smith Frida, Browall Maria

机构信息

Department of Nursing, School of Health and Welfare, Jönköping University, Jönköping, Sweden.

School of Research, School of Health and Welfare, Jönköping University, Jönköping, Sweden.

出版信息

Support Care Cancer. 2025 Aug 12;33(9):781. doi: 10.1007/s00520-025-09798-8.

Abstract

PURPOSE

A cancer diagnosis and treatment pose significant physical and psychological challenges. The study aimed to explore factors associated with distress over time in women diagnosed with breast cancer undergoing radiotherapy (RT) with access to a digital information tool, specifically examining if factors such as health literacy and self-efficacy had any influence on distress.

METHODS

In this pilot randomised controlled trial, women were assigned to an intervention group (n = 59) with access to a digital information tool or a control group (n = 52). Assessments were conducted at baseline, one week before RT (FU1), one week post- (FU2), and six months after treatment (FU3). Distress was measured at all time points, and associated factors were evaluated at baseline and six months.

RESULTS

In the intervention group, a statistically significant reduction in distress was observed over time (FU1, p = .009; FU2, p < .001; FU3, p < .001). The control group showed a significant reduction at FU3 (p = .009). Quade's ANCOVA revealed no significant differences between the groups in distress prevalence (F = 3.460, p = .066). No significant changes in health literacy or self-efficacy were observed over time.

CONCLUSION

The results indicate no statistically significant effect on distress; however, there is a potential indication of a reduction in distress, suggesting that the digital information tool may offer some benefits. Further research is required to confirm this relationship.

摘要

目的

癌症的诊断和治疗带来了重大的身体和心理挑战。本研究旨在探讨接受放射治疗(RT)的乳腺癌女性患者在一段时间内与痛苦相关的因素,这些患者可以使用数字信息工具,具体研究健康素养和自我效能等因素是否对痛苦有任何影响。

方法

在这项试点随机对照试验中,女性被分配到可以使用数字信息工具的干预组(n = 59)或对照组(n = 52)。在基线、放疗前一周(FU1)、放疗后一周(FU2)和治疗后六个月(FU3)进行评估。在所有时间点测量痛苦程度,并在基线和六个月时评估相关因素。

结果

在干预组中,随着时间的推移,痛苦程度在统计学上有显著降低(FU1,p = .009;FU2,p < .001;FU3,p < .001)。对照组在FU3时显示出显著降低(p = .009)。Quade的协方差分析显示,两组在痛苦患病率上没有显著差异(F = 3.460,p = .066)。随着时间的推移,未观察到健康素养或自我效能有显著变化。

结论

结果表明对痛苦没有统计学上的显著影响;然而,有潜在迹象表明痛苦有所减轻,这表明数字信息工具可能有一些益处。需要进一步的研究来证实这种关系。

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