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基于离心收缩的抗阻运动对慢性卒中患者身体机能的影响:一项随机对照试验。

Effects of eccentric contraction-based resistance exercise on physical performance in chronic stroke patients: A randomized controlled trial.

作者信息

Kim Younji, Oh Seunglyul, Kim Dae Young, Lim Jae-Young

机构信息

Department of Rehabilitation Medicine, School of Medicine, Ewha Woman's University Seoul Hospital, Seoul, Republic of Korea.

Research Institute, Hospi Co., Ltd, Hanam, Republic of Korea.

出版信息

Medicine (Baltimore). 2025 Aug 8;104(32):e43491. doi: 10.1097/MD.0000000000043491.

DOI:10.1097/MD.0000000000043491
PMID:40797445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12338267/
Abstract

BACKGROUND

Chronic stroke patients often experience muscle weakness, reduced mobility, and impaired physical function. Eccentric contraction-based resistance exercise has been proposed as an effective intervention to improve neuromuscular function and mobility; however, its effects remain unclear. This study compared the effects of eccentric overload resistance training using a flywheel device and traditional resistance training on physical performance and muscle strength in chronic stroke patients.

METHODS

This 8-week, randomized controlled trial included chronic stroke patients who were assigned to either an intervention group (INT; eccentric flywheel-based resistance exercise) or a control group (CON; conventional resistance training). Physical function was assessed based on the timed up-and-go test, 6-minute walk test, 5-times sit-to-stand test, gait speed, and isokinetic muscle strength before and after the intervention.

RESULTS

Of the 40 participants enrolled, 36 completed the study (INT group: n = 18; CON group: n = 18). Both groups showed improvements in physical function outcomes, such as gait speed, balance, and functional mobility, postintervention. Muscle strength also improved in both groups, with no significant between-group differences in functional or muscle strength outcomes. Subgroup analysis revealed additional benefits of eccentric training for participants with limited walking ability.

CONCLUSION

Both resistance training approaches improved physical performance in chronic stroke patients. However, eccentric overload resistance training offered additional advantages in functional mobility, particularly for patients with severe impairments. Both eccentric overload and traditional resistance training significantly improved physical performance in chronic stroke patients, highlighting the importance of structured exercise in rehabilitation.

摘要

背景

慢性中风患者常出现肌肉无力、活动能力下降和身体功能受损。基于离心收缩的抗阻运动已被提出作为改善神经肌肉功能和活动能力的有效干预措施;然而,其效果仍不明确。本研究比较了使用飞轮装置的离心超负荷抗阻训练与传统抗阻训练对慢性中风患者身体表现和肌肉力量的影响。

方法

这项为期8周的随机对照试验纳入了慢性中风患者,这些患者被分配到干预组(INT;基于飞轮的离心抗阻运动)或对照组(CON;传统抗阻训练)。在干预前后,根据定时起立行走测试、6分钟步行测试、5次坐立测试、步态速度和等速肌肉力量评估身体功能。

结果

在纳入的40名参与者中,36名完成了研究(INT组:n = 18;CON组:n = 18)。两组在干预后身体功能指标均有改善,如步态速度、平衡和功能性活动能力。两组的肌肉力量也有所提高,在功能或肌肉力量指标上两组间无显著差异。亚组分析显示,离心训练对步行能力有限的参与者有额外益处。

结论

两种抗阻训练方法均改善了慢性中风患者的身体表现。然而,离心超负荷抗阻训练在功能性活动能力方面具有额外优势,尤其是对严重受损的患者。离心超负荷训练和传统抗阻训练均显著改善了慢性中风患者的身体表现,突出了结构化运动在康复中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0764/12338267/83b09b443be0/medi-104-e43491-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0764/12338267/2982cbdfa088/medi-104-e43491-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0764/12338267/83b09b443be0/medi-104-e43491-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0764/12338267/2982cbdfa088/medi-104-e43491-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0764/12338267/83b09b443be0/medi-104-e43491-g002.jpg

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Effects of eccentric contraction-based resistance exercise on physical performance in chronic stroke patients: A randomized controlled trial.基于离心收缩的抗阻运动对慢性卒中患者身体机能的影响:一项随机对照试验。
Medicine (Baltimore). 2025 Aug 8;104(32):e43491. doi: 10.1097/MD.0000000000043491.

本文引用的文献

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J Clin Med. 2023 Jan 10;12(2):550. doi: 10.3390/jcm12020550.
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Applications of Eccentric Exercise to Improve Muscle and Mobility Function in Older Adults.离心运动在改善老年人肌肉和活动功能方面的应用。
Ann Geriatr Med Res. 2022 Mar;26(1):4-15. doi: 10.4235/agmr.21.0138. Epub 2022 Jan 18.
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Effects of Flywheel Resistance Training on Sport Actions. A Systematic Review and Meta-Analysis.飞轮阻力训练对运动动作的影响:一项系统评价与荟萃分析
J Hum Kinet. 2021 Jan 30;77:191-204. doi: 10.2478/hukin-2021-0020. eCollection 2021 Jan.
4
Eccentric training effects for patients with post-stroke hemiparesis on strength and speed gait: A randomized controlled trial.偏心训练对脑卒中偏瘫患者的力量和速度步态的影响:一项随机对照试验。
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Advances and challenges in stroke rehabilitation.脑卒中康复的进展与挑战。
Lancet Neurol. 2020 Apr;19(4):348-360. doi: 10.1016/S1474-4422(19)30415-6. Epub 2020 Jan 28.
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Effects of Eccentric-Focused Versus Conventional Training on Lower Limb Muscular Strength in Older People: A Systematic Review With Meta-Analysis.离心聚焦训练与传统训练对老年人下肢肌肉力量的影响:一项Meta分析的系统评价
J Aging Phys Act. 2019 Dec 1;27(4):823-830. doi: 10.1123/japa.2018-0294.
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Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.全球、区域和国家卒中负担,1990-2016 年:2016 年全球疾病负担研究的系统分析。
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Strength and Step Activity After Eccentric Resistance Training in Those With Incomplete Spinal Cord Injuries.不完全性脊髓损伤患者进行离心抗阻训练后的力量和步行活动
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Exp Gerontol. 2017 Nov;98:224-229. doi: 10.1016/j.exger.2017.08.034. Epub 2017 Sep 6.
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Validity and reliability of a performance evaluation tool based on the modified Barthel Index for stroke patients.基于改良巴氏指数的脑卒中患者绩效评估工具的有效性和可靠性。
BMC Med Res Methodol. 2017 Aug 25;17(1):131. doi: 10.1186/s12874-017-0409-2.