阿莫西林与头孢曲松治疗阿莫西林不敏感所致肺炎的对比
Amoxicillin vs. ceftriaxone to treat pneumonia caused by amoxicillin-non-susceptible .
作者信息
Musher Daniel M
机构信息
Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Department of Microbiology and Molecular Virology, Baylor College of Medicine, Houston, Texas, USA.
出版信息
Antimicrob Agents Chemother. 2025 Sep 3;69(9):e0078025. doi: 10.1128/aac.00780-25. Epub 2025 Aug 13.
Although the article by J Càmara, I Grau, A González-Díaz, N Santos, et al. (Antimicrob Agents Chemother 69:e00237-25, 2025, https://doi.org/10.1128/aac.00237-25) suggests that ceftriaxone is greatly superior to amoxicillin in treating pneumonia due to pneumococci with an MIC > 2 mg/L, much of the difference in efficacy of the two drugs may have been due to dosage, route, and times of administration of the amoxicillin.
尽管J·卡马拉、I·格劳、A·冈萨雷斯-迪亚兹、N·桑托斯等人发表于《抗菌药物与化疗》（2025年，第69卷：e00237 - 25，https://doi.org/10.1128/aac.00237 - 25）的文章表明，对于肺炎链球菌最低抑菌浓度（MIC）>2 mg/L的肺炎，头孢曲松在治疗效果上远优于阿莫西林，但这两种药物疗效上的大部分差异可能归因于阿莫西林的剂量、给药途径和给药次数。
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