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PFNA-II治疗股骨转子间骨折(AO/OTA 31 A1和A2型)时植入失败的危险因素。

Risk factors for implant failure of PFNA-II in the treatment of intertrochanteric fractures (AO/OTA 31 A1 and A2).

作者信息

Li Zijian, Gao Jianpeng, Wu Xiaoyong, Chang Zhengyang, Liu Xiao, Zhang Licheng, Li Ming, Nie Shaobo

机构信息

Department of Orthopaedics, The Fourth Medical Center of the Chinese PLA General Hospital, Beijing, 100853, China.

Medical School of Chinese PLA, Beijing, China.

出版信息

BMC Musculoskelet Disord. 2025 Aug 13;26(1):784. doi: 10.1186/s12891-025-09035-7.

Abstract

BACKGROUND

Intertrochanteric fractures are common in the elderly, with PFNA being the primary treatment. The shorter PFNA-II is frequently used in Asian populations, but its failure risk factors remain unclear. This study aims to explore these factors to guide clinical treatment.

METHODS

A retrospective study was conducted on 693 intertrochanteric fracture patients treated with PFNA-II. Patients were divided into two groups based on implant failure. Reduction quality, continuity of the medial femoral cortex, nail length, and tip apex distance (TAD) were analyzed to determine risk factors.

RESULTS

A total of 466 patients were enrolled, with an average age of 83 years old. There were 24 patients with implant failure. There was no significant difference in demographic index between the two groups. After propensity score matching and multivariate logistic regression analysis, there were statistically significant differences in reduction quality and continuity of the medial femoral cortex between the two groups. Poor reduction quality significantly increased the risk of implant failure by 22.2 times, while discontinuity of the medial femoral cortex increased this risk by 12.1 times.

CONCLUSION

Poor reduction quality and medial femoral cortex discontinuity are key risk factors for implant failure in intertrochanteric fractures treated with short PFNA-II, increasing failure risk by 22.2 and 12.1 times respectively. Anatomic reduction and medial support reconstruction are crucial for successful outcomes.

摘要

背景

股骨转子间骨折在老年人中很常见,股骨近端防旋髓内钉(PFNA)是主要的治疗方法。较短的PFNA-II常用于亚洲人群,但其失败的危险因素仍不清楚。本研究旨在探讨这些因素以指导临床治疗。

方法

对693例接受PFNA-II治疗的股骨转子间骨折患者进行回顾性研究。根据内固定失败情况将患者分为两组。分析复位质量、股骨内侧皮质连续性、髓内钉长度和尖顶距(TAD)以确定危险因素。

结果

共纳入466例患者,平均年龄83岁。有24例内固定失败患者。两组患者的人口统计学指标无显著差异。经过倾向评分匹配和多因素逻辑回归分析,两组患者在复位质量和股骨内侧皮质连续性方面存在统计学显著差异。复位质量差使内固定失败风险显著增加22.2倍,而股骨内侧皮质不连续使该风险增加12.1倍。

结论

复位质量差和股骨内侧皮质不连续是短PFNA-II治疗股骨转子间骨折内固定失败的关键危险因素,分别使失败风险增加22.2倍和12.1倍。解剖复位和内侧支撑重建对于获得成功的治疗结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d3/12344898/a20782a52f82/12891_2025_9035_Fig1_HTML.jpg

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