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犬皮肤无力症。两例报告。

Cutaneous asthenia in the dog. A report of two cases.

作者信息

Poulsen P H, Thomsen M K, Kristensen F

出版信息

Nord Vet Med. 1985 Sep-Oct;37(5):291-7.

PMID:4080535
Abstract

Two cases of cutaneous asthenia in Danish dogs are described. Case 1 was a Weimeraner; case 2 a Golden Retriever. In both instances the dogs had acquired numerous lesions of the skin within the first half year of their lives. The wounds exhibited good healing but led to broad, thin and pliable scars. Both dogs had in several instances received attention to gaping wounds, characterized by little tendency of bleeding. The clinical examination reveiled that the skin was hyperextensible and possessed pendulous folds, particularly behind the elbows. The degree of hyperextensibility was evaluated by means of a skin extensibility index. Furthermore, it was possible to manipulate the digital cushion in an unphysiological manner. One of the dogs were euthanised, and in case 2 the clinical diagnosis was confirmed by histopathological examination. No conclusion could be drawn regarding the mode of inheritance in the two cases, but existing literature strongly suggests the existence of a genetic disposition and thus, elimination of the disease related gene from any breeding program is of great importance.

摘要

描述了两例丹麦犬皮肤松弛症病例。病例1是一只威玛猎犬;病例2是一只金毛寻回犬。在这两个病例中,狗在出生后的前半年内身上出现了大量皮肤损伤。伤口愈合良好,但形成了宽大、薄且柔韧的疤痕。两只狗都曾多次因伤口裂开而接受治疗,其特点是出血倾向小。临床检查发现皮肤过度伸展,有下垂的褶皱,尤其是在肘部后面。通过皮肤伸展指数评估皮肤过度伸展的程度。此外,还可以以非生理性的方式操作指垫。其中一只狗实施了安乐死,病例2通过组织病理学检查确诊。关于这两个病例的遗传方式无法得出结论,但现有文献强烈表明存在遗传倾向,因此,在任何育种计划中消除与该疾病相关的基因非常重要。

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