Iwaisako Natsuno, Oura Shoji
Department of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, JPN.
Cureus. 2025 Jul 15;17(7):e88024. doi: 10.7759/cureus.88024. eCollection 2025 Jul.
A 49-year-old woman had undergone radiofrequency ablation (RFA) therapy and sentinel lymph node biopsy (SNB), followed by radiation therapy for her right breast cancer at the age of 31. The patient had further undergone nipple-sparing mastectomy (NSM), SNB, and immediate breast reconstruction using an extended latissimus dorsi musculocutaneous flap (eLDMCF) for her left breast cancer at the age of 43. Follow-up mammography further revealed widespread linear calcifications in the right breast. Core needle biopsy pathologically showed atypical cells growing in trabecular and tubular fashions with connective tissue proliferation, leading to the diagnosis of invasive ductal carcinoma. Due to the patient's strong preference for not using silicone prosthesis on right breast reconstruction, the patient underwent NSM and SNB, followed by immediate breast reconstruction using the right eLDMCF after obtaining full informed consent about the unknown bilateral eLDMCF harvesting effect on respiratory function. The patient recovered uneventfully and showed respiratory function as follows: preoperative 2.69 L to postoperative 2.46 L in vital capacity and preoperative 2.1 L to postoperative 1.83 L in forced expiratory volume in one second. The patient reported no respiratory symptoms and has been fully satisfied with the cosmetic outcomes of the reconstructed right breast. These results suggest that bilateral breast reconstruction using eLDMCFs can be a good therapeutic option for metachronous bilateral breast cancer.
一名49岁女性在31岁时接受了射频消融(RFA)治疗和前哨淋巴结活检(SNB),随后对其右乳腺癌进行了放射治疗。该患者在43岁时又因左乳腺癌接受了保留乳头的乳房切除术(NSM)、SNB,并使用背阔肌肌皮瓣(eLDMCF)进行了即刻乳房重建。后续乳房X线摄影进一步显示右乳有广泛的线性钙化。粗针活检病理显示非典型细胞呈小梁状和管状生长,伴有结缔组织增生,诊断为浸润性导管癌。由于患者强烈倾向于右乳重建不使用硅胶假体,在充分了解双侧eLDMCF采集对呼吸功能的未知影响并获得充分知情同意后,患者接受了NSM和SNB,随后使用右侧eLDMCF进行了即刻乳房重建。患者恢复顺利,呼吸功能如下:肺活量术前2.69升,术后2.46升;一秒用力呼气量术前2.1升,术后1.83升。患者未报告呼吸症状,对右乳重建的美容效果非常满意。这些结果表明,使用eLDMCF进行双侧乳房重建对于异时性双侧乳腺癌可能是一种很好的治疗选择。