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Intranasal mRNA vaccines: Targeting mucosal immunity through optimized delivery.

作者信息

Pandey Achyut, Kumar Sacheen, Mishra Shruti

机构信息

School of Biosciences & Technology, Galgotias University, Greater Noida, Gautam Buddha Nagar, Uttar Pradesh 203201, India.

出版信息

Mol Ther Nucleic Acids. 2025 Aug 8;36(3):102654. doi: 10.1016/j.omtn.2025.102654. eCollection 2025 Sep 9.

DOI:10.1016/j.omtn.2025.102654
PMID:40822028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12355067/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b297/12355067/fbe8ac018f33/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b297/12355067/fbe8ac018f33/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b297/12355067/fbe8ac018f33/gr1.jpg

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[1]
Intranasal mRNA vaccines: Targeting mucosal immunity through optimized delivery.

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[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
[Research progress on nasal mucosal immunity and intranasal vaccines].

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[9]
Enhanced mucosal SARS-CoV-2 immunity after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.

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[10]
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本文引用的文献

[1]
Deconvolution of cargo delivery and immunogenicity following intranasal delivery of mRNA lipid nanoparticle vaccines.

Mol Ther Nucleic Acids. 2025-4-24

[2]
Intranasal prime-boost RNA vaccination elicits potent T cell response for lung cancer therapy.

Signal Transduct Target Ther. 2025-3-24

[3]
Enhanced mucosal SARS-CoV-2 immunity after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.

Mol Ther. 2024-12-4

[4]
Charge-assisted stabilization of lipid nanoparticles enables inhaled mRNA delivery for mucosal vaccination.

Nat Commun. 2024-11-2

[5]
Recent Advances in Lipid Nanoparticles and Their Safety Concerns for mRNA Delivery.

Vaccines (Basel). 2024-10-8

[6]
mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applications.

J Biomed Sci. 2023-10-7

[7]
Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection.

Sci Adv. 2023-9-22

[8]
Recent Advancement in mRNA Vaccine Development and Applications.

Pharmaceutics. 2023-7-18

[9]
Lipid nanoparticles for mRNA delivery.

Nat Rev Mater. 2021

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