Du Yuxin, He Zongqi
Department of Anorectal Surgery, Kunshan Hospital Affiliated to Nanjing University of Chinese Medicine, Kunshan, CHN.
Cureus. 2025 Jul 18;17(7):e88235. doi: 10.7759/cureus.88235. eCollection 2025 Jul.
Central diabetes insipidus (CDI) is a rare endocrine disorder that can pose significant risks in the perioperative setting, especially when routine fasting and fluid restriction are applied. We report the case of a 34-year-old man with a history of CDI who underwent surgical drainage of a perianal abscess and subsequently developed severe hypernatremia and neurological symptoms due to postoperative water restriction. Prompt fluid resuscitation and endocrinology consultation led to rapid recovery. This case underscores the importance of early recognition and individualized perioperative management, including desmopressin replacement and tailored fluid strategies in CDI patients undergoing surgery.
中枢性尿崩症(CDI)是一种罕见的内分泌疾病,在围手术期会带来重大风险,尤其是在实施常规禁食和液体限制时。我们报告了一例34岁患有中枢性尿崩症的男性患者,该患者接受了肛周脓肿手术引流,随后因术后限制饮水而出现严重高钠血症和神经症状。及时的液体复苏和内分泌科会诊促使其迅速康复。该病例强调了早期识别和个体化围手术期管理的重要性,包括对接受手术的中枢性尿崩症患者进行去氨加压素替代治疗和制定个性化的液体策略。