Clapp Benjamin, Farsi Soroush, Roberson Laura, Proksch Daisy, Lloyd S Julie-Ann, Billy Helmuth T
Department of Surgery, Bariatric and Minimally Invasive Surgery, Texas Tech HSC Paul Foster School of Medicine, El Paso, TX.
Department of Surgery, General Surgery Resident, Community Memorial Hospital, Ventura, CA.
Surg Laparosc Endosc Percutan Tech. 2025 Aug 25. doi: 10.1097/SLE.0000000000001402.
Marginal ulcer (MU) remains a serious complication after Roux-en-Y gastric bypass (RYGB). This can be a life-threatening problem, even years after RYGB. Patients can present with pain or even with hemorrhage or perforation. There is no agreed-upon standard in prevention or treatment, although most perforated ulcers are treated with an omental patch. We present our results of treatment of MU with truncal vagotomy (TV).
A retrospective chart review identified patients who required surgical intervention for nonhealing MU or those presenting with perforated MU. Free perforation was treated with surgical intervention at the time of presentation. In patients with recalcitrant MU (without perforation), preoperative upper endoscopy confirmed the diagnosis. In all cases, the gastrojejunal anastomosis was revised or the marginal ulcer was resected, followed by laparoscopic TV. We reviewed operative time, ulcer recurrence, and complications in the cases identified.
Forty-two patients underwent revision/resection following presentation with a recalcitrant ulcer or free perforation of a MU. Concomitant TV was performed in all cases. Average time from the RYGB was 71.8 months. There were no 30-day mortalities and no leaks. Average follow-up was 21 months. Sixty-two percent of patients had a follow-up endoscopy by 1 year with no recurrences. There were no reoperations or major complications.
Marginal ulceration remains a common complication after Roux-en-Y gastric bypass. Medical therapy is the first-line therapy but some patients will go on to develop refractory disease. This can be chronic, or acute with perforation or hemorrhage. Laparoscopic truncal vagotomy with revision of the gastrojejunal anastomosis is safe and effective in the treatment of marginal ulcers with low recurrence rates.
边缘性溃疡(MU)仍是Roux-en-Y胃旁路术(RYGB)后一种严重的并发症。这可能是一个危及生命的问题,甚至在RYGB术后数年也是如此。患者可能出现疼痛,甚至出血或穿孔。尽管大多数穿孔性溃疡采用网膜补片治疗,但在预防或治疗方面尚无公认的标准。我们展示了采用迷走神经干切断术(TV)治疗MU的结果。
通过回顾性病历审查确定因MU不愈合或穿孔而需要手术干预的患者。游离穿孔在就诊时即进行手术干预。对于顽固性MU(无穿孔)患者,术前上消化道内镜检查确诊。在所有病例中,均对胃空肠吻合口进行修复或切除边缘性溃疡,随后行腹腔镜TV。我们回顾了所确定病例的手术时间、溃疡复发情况及并发症。
42例患者因顽固性溃疡或MU游离穿孔就诊后接受了修复/切除术。所有病例均同时进行了TV。距RYGB的平均时间为71.8个月。无30天内死亡病例,也无渗漏。平均随访时间为21个月。62%的患者在1年时接受了随访内镜检查,无复发。无再次手术或重大并发症。
边缘性溃疡仍是Roux-en-Y胃旁路术后常见的并发症。药物治疗是一线治疗方法,但一些患者会发展为难治性疾病。这可能是慢性的,也可能是急性的,伴有穿孔或出血。腹腔镜迷走神经干切断术联合胃空肠吻合口修复术治疗边缘性溃疡安全有效,复发率低。