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介绍可流动树脂复合材料作为游离龈瓣移植术后一种新型的腭部敷料:一项随机临床试验。

Introducing flowable resin composite as a novel palatal dressing after free gingival graft harvesting: a randomized clinical trial.

作者信息

Temraz Mohamed Elsayed, Shemais Nesma, Khalil Eman, Ghalwash Dalia, Elbarbary Ahmed

机构信息

Oral Medicine and Periodontology Department, Faculty of Dentistry, The British University in Egypt, El- Sherouk City, Egypt.

Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.

出版信息

BDJ Open. 2025 Aug 25;11(1):75. doi: 10.1038/s41405-025-00362-4.

DOI:10.1038/s41405-025-00362-4
PMID:40854876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12378967/
Abstract

OBJECTIVES

This study aimed to evaluate the effectiveness of using a flowable resin composite compared to periodontal pack in reducing postoperative morbidity after free gingival graft (FGG) harvesting.

MATERIALS AND METHODS

In this randomized controlled clinical trial, 34 patients requiring FGG were allocated into two equal groups. The intervention group received a flowable resin composite dressing over the palatal wound, while the control group received Coe-Pak. Postoperative pain was assessed using a Visual Analogue Scale (VAS) and mean analgesic consumption over 14 days. Secondary outcomes included wound size and color match of the healing site assessed at weeks 1, 2, 3, and 6.

RESULTS

The control group reported significantly higher VAS pain scores than the intervention group on days 1-4 and 10 (p < 0.05), and highly significant differences on days 5, 6, 8, and 9 (p < 0.001). Analgesic use decreased significantly in both groups (p < 0.001), with no intergroup differences. Wound size and color match improvements were comparable between groups.

CONCLUSION

The application of flowable resin composite significantly reduces early postoperative pain following FGG harvesting without compromising healing outcomes. Its ease of application, patient comfort, and comparable clinical performance make it a promising alternative to traditional dressings. However, further investigations are warranted to confirm the biocompatibility of flowable resin composites and their impact on soft tissue healing.

摘要

目的

本研究旨在评估与牙周塞治剂相比,使用可流动树脂复合材料在减少游离龈瓣移植术(FGG)术后发病率方面的有效性。

材料与方法

在这项随机对照临床试验中,34例需要进行FGG的患者被平均分为两组。干预组在腭部伤口上使用可流动树脂复合材料敷料,而对照组使用Coe - Pak。使用视觉模拟量表(VAS)评估术后疼痛,并记录14天内的平均镇痛药消耗量。次要结局包括在第1、2、3和6周评估的伤口大小和愈合部位的颜色匹配情况。

结果

在第1 - 4天和第10天,对照组报告的VAS疼痛评分显著高于干预组(p < 0.05),在第5、6、8和9天有极显著差异(p < 0.001)。两组的镇痛药使用量均显著减少(p < 0.001),组间无差异。两组间伤口大小和颜色匹配的改善情况相当。

结论

可流动树脂复合材料的应用显著降低了FGG术后的早期疼痛,且不影响愈合结果。其易于应用、患者舒适度高以及可比的临床性能使其成为传统敷料的一个有前景的替代方案。然而,需要进一步研究以确认可流动树脂复合材料的生物相容性及其对软组织愈合的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/def8ec31d0d8/41405_2025_362_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/4a94946a5c3c/41405_2025_362_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/60bfaa1feedf/41405_2025_362_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/d5a124e64213/41405_2025_362_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/ee265cca0f21/41405_2025_362_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/def8ec31d0d8/41405_2025_362_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/4a94946a5c3c/41405_2025_362_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/60bfaa1feedf/41405_2025_362_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/d5a124e64213/41405_2025_362_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/ee265cca0f21/41405_2025_362_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091e/12378967/def8ec31d0d8/41405_2025_362_Fig5_HTML.jpg

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本文引用的文献

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Volumetric assessment of volume stable collagen matrix in maxillary single implant site development: A randomized controlled clinical trial.上颌单牙种植位点开发中体积稳定胶原基质的容积评估:一项随机对照临床试验。
Clin Implant Dent Relat Res. 2024 Oct;26(5):930-941. doi: 10.1111/cid.13353. Epub 2024 Jun 27.
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Effect of collagen sponge and flowable resin composite on pain management after free gingival graft harvesting: A randomized controlled clinical trial.
胶原海绵和流动性树脂复合材料对游离牙龈移植术后疼痛管理的影响:一项随机对照临床试验。
Eur J Oral Sci. 2023 Jun;131(3):e12935. doi: 10.1111/eos.12935. Epub 2023 May 11.
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Wound healing dynamics, morbidity, and complications of palatal soft-tissue harvesting.腭部软组织采集的伤口愈合动态、发病率及并发症
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