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新生儿中心静脉导管经中心静脉和股静脉置入的应用:法国新生儿重症监护病房实践的全国性调查

Use of centrally and femorally inserted central venous catheters in neonates: a nationwide survey of practices in French neonatal intensive care units.

作者信息

Lanel Penelope, Bonnel Martin, Teillet Baptiste, Bellanger Claire, Kermorvant-Duchemin Elsa, Lapillonne Alexandre, Sartorius Victor

机构信息

Department of neonatal intensive care, Hôpital Necker-Enfants malades, AP-HP, Paris, France.

Université Paris Cité, Paris, France.

出版信息

Eur J Pediatr. 2025 Aug 26;184(9):575. doi: 10.1007/s00431-025-06375-3.

DOI:10.1007/s00431-025-06375-3
PMID:40856778
Abstract

UNLABELLED

The aim of this study is to assess the use of centrally and femorally inserted central catheters (CICCs and FICCs, respectively) in French neonatal intensive care units (NICUs) and to describe associated clinical practices. We conducted a national cross-sectional survey targeting all level III or higher NICUs in France. A link to an online questionnaire was sent to one member of the medical team in each unit between September and December 2024. CICCs were defined as central catheters inserted via the brachiocephalic or the internal jugular vein, and FICCs as central catheters inserted via the common femoral vein. All 65 NICUs participated in the survey. Of these, 45 (69.2%) reported performing CICC or FICC placements. Specifically, 35 (53.8%), 39 (60.0%), and 37 (56.9%) units performed insertions via the brachiocephalic vein, internal jugular vein, and common femoral vein, respectively. In most units, CICC/FICCs were used most frequently (n = 20) or systematically (n = 18) as a second-line option after an epicutaneo-caval catheter had been considered. In units that use CICC/FICCs, placement was performed by a NICU physician in 39 (86.7%) of them. In most cases, the catheter was placed under conscious sedation when feasible. The median minimum patient weight [interquartile range] considered suitable for central catheter placement was 1500 [800-2000] grams for brachiocephalic catheters, 1500 [900-2000] grams for internal jugular catheters, and 1650 [800-2000] grams for common femoral catheters. Very small caliber catheters (1 or 2 French in diameter) and a modified Seldinger insertion technique were used in 23 and 17 units, respectively.

CONCLUSION

CICC/FICCs use is part of clinical practice in most French NICUs, mainly as a second-line option. Indications for use, placement techniques, and maintenance protocols vary across units.

WHAT IS KNOWN

• Previous studies from specialized centers have shown that centrally and femorally inserted central catheters (CICC/FICCs) can be safely inserted in neonates. •It is still unclear to what extent these practices have been implemented in neonatal intensive care units.

WHAT IS NEW

• CICC/FICCs are now part of clinical practice in the majority of French NICUs. • The median minimum weight for CICC/FICC insertion was approximately 1500 g, indicating that their use has extended to smaller, more vulnerable infants. Very small-diameter catheters combined with a modified insertion technique enhance compatibility with neonatal vasculature.

摘要

未标注

本研究旨在评估法国新生儿重症监护病房(NICUs)中经中心静脉和股静脉插入的中心静脉导管(分别为CICC和FICC)的使用情况,并描述相关的临床实践。我们针对法国所有三级及以上的NICUs进行了一项全国性横断面调查。2024年9月至12月期间,向每个单位的一名医疗团队成员发送了一份在线问卷链接。CICC被定义为经头臂静脉或颈内静脉插入的中心静脉导管,FICC被定义为经股总静脉插入的中心静脉导管。所有65个NICUs都参与了调查。其中,45个(69.2%)报告进行了CICC或FICC置管。具体而言,分别有35个(53.8%)、39个(60.0%)和37个(56.9%)单位通过头臂静脉、颈内静脉和股总静脉进行置管。在大多数单位中,CICC/FICC最常(n = 20)或系统地(n = 18)作为在考虑使用经皮腔静脉导管后的二线选择。在使用CICC/FICC的单位中,39个(86.7%)由NICU医生进行置管。在大多数情况下,可行时在清醒镇静下放置导管。对于头臂静脉导管,认为适合中心静脉导管置管的最小患者体重中位数[四分位间距]为1500[800 - 2000]克,颈内静脉导管为1500[900 - 2000]克,股总静脉导管为1650[800 - 2000]克。分别有23个和17个单位使用了非常小口径的导管(直径为1或2法国规格)和改良的Seldinger插入技术。

结论

在大多数法国NICUs中,CICC/FICC的使用是临床实践的一部分,主要作为二线选择。各单位的使用指征、置管技术和维护方案各不相同。

已知信息

• 来自专业中心的先前研究表明,经中心静脉和股静脉插入的中心静脉导管(CICC/FICC)可安全地插入新生儿体内。• 这些实践在新生儿重症监护病房中的实施程度仍不清楚。

新发现

• CICC/FICC现在是大多数法国NICUs临床实践的一部分。• CICC/FICC插入的最小体重中位数约为1500克,这表明其使用已扩展到更小、更脆弱的婴儿。非常小直径的导管与改良的插入技术相结合,增强了与新生儿血管系统的兼容性。

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本文引用的文献

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Catheter-related Internal Jugular Vein Thrombosis in Neonates and Long-term Consequences: A Prospective Cohort Study.
Anesthesiology. 2025 Feb 1;142(2):298-307. doi: 10.1097/ALN.0000000000005250. Epub 2024 Oct 4.
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Ultrasound-Guided Centrally Inserted Central Catheter (CICC) Placement in Newborns: A Safe Clinical Training Program in a Neonatal Intensive Care Unit.超声引导下新生儿中心静脉导管(CICC)的中心置入:新生儿重症监护病房的一项安全临床培训项目
Children (Basel). 2024 Mar 26;11(4):395. doi: 10.3390/children11040395.
3
Cyanoacrylate glue as part of a new bundle to decrease neonatal PICC-related complications.氰基丙烯酸酯胶作为减少新生儿经外周中心静脉置管相关并发症新方案的一部分。
Eur J Pediatr. 2023 Dec;182(12):5607-5613. doi: 10.1007/s00431-023-05253-0. Epub 2023 Oct 10.
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The neonatal DAV-expert algorithm: a GAVeCeLT/GAVePed consensus for the choice of the most appropriate venous access in newborns.新生儿 DAV 专家算法:GAVeCeLT/GAVePed 共识选择新生儿最合适的静脉通路。
Eur J Pediatr. 2023 Aug;182(8):3385-3395. doi: 10.1007/s00431-023-04984-4. Epub 2023 May 17.
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Chest-to-arm tunneling technique for central venous access devices in neonates.新生儿中心静脉通路装置的胸臂隧道技术
J Vasc Access. 2024 May;25(3):988-994. doi: 10.1177/11297298231174064. Epub 2023 May 7.
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US-guided central venous catheter placement in the neonatal intensive care unit: Brachiocephalic vein or internal jugular vein?超声引导下新生儿重症监护病房中心静脉置管:头臂静脉还是颈内静脉?
J Vasc Access. 2024 Jul;25(4):1164-1169. doi: 10.1177/11297298231152679. Epub 2023 Feb 7.
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Rapid Superficial Vein Assessment (RaSuVA): A pre-procedural systematic evaluation of superficial veins to optimize venous catheterization in neonates.快速浅层静脉评估(RaSuVA):一种在新生儿中优化静脉置管的术前系统评估浅层静脉的方法。
J Vasc Access. 2024 Jan;25(1):303-307. doi: 10.1177/11297298221098481. Epub 2022 May 20.
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A GAVeCeLT bundle for central venous catheterization in neonates and children: A prospective clinical study on 729 cases.用于新生儿和儿童中心静脉置管的GAVeCeLT套件:729例前瞻性临床研究。
J Vasc Access. 2023 Nov;24(6):1477-1488. doi: 10.1177/11297298221074472. Epub 2022 May 9.
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Peripherally inserted central catheters versus non-tunnelled ultrasound-guided central venous catheters in newborns: a retrospective observational study.新生儿外周静脉穿刺中心静脉导管与非隧道式超声引导中心静脉导管的比较:一项回顾性观察研究
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The intracavitary ECG method for tip location of ultrasound-guided centrally inserted central catheter in neonates.经胸心内电图法在超声引导下确定新生儿中心静脉置管尖端位置。
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