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基于近红外多光谱图像融合技术的散射组织成像

Imaging Through Scattering Tissue Based on NIR Multispectral Image Fusion Technique.

作者信息

Atiya Nisan, Shemer Amir, Schwarz Ariel, Beiderman Yevgeny, Danan Yossef

机构信息

Department of Electrical and Electronics Engineering, Azrieli College of Engineering, Jerusalem 9103501, Israel.

Faculty of Electrical and Electronics Engineering, Holon Institute of Technology, Holon 5810201, Israel.

出版信息

Sensors (Basel). 2025 Aug 12;25(16):4977. doi: 10.3390/s25164977.

DOI:10.3390/s25164977
PMID:40871840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12390302/
Abstract

Non-invasive diagnostics play a crucial role in medicine, and they ensure both contamination safety and patient comfort. The proposed study integrates hyperspectral imaging with advanced image fusion, enabling non-invasive, diagnostic procedure within tissue. It utilizes near-infrared (NIR) wavelength vision that is suitable for reflections from objects within a dispersive layer, enabling the reconstruction of internal tissue layers images. It can detect objects, including cancerous tumors (presented as phantoms), inside human tissue. This involves processing data from multiple images taken in different NIR bands and merging them through image fusion techniques. Our research demonstrates evident data about objects within the diffusive media, visible only in the reconstructed images. The experimental results demonstrate a significant correlation with the samples employed in the study's experimental design.

摘要

非侵入性诊断在医学中发挥着至关重要的作用,它既能确保无污染安全又能让患者感到舒适。拟议的研究将高光谱成像与先进的图像融合技术相结合,能够在组织内进行非侵入性诊断程序。它利用近红外(NIR)波长视觉,适用于色散层内物体的反射,从而能够重建内部组织层图像。它可以检测人体组织内的物体,包括癌性肿瘤(以体模形式呈现)。这涉及处理在不同近红外波段拍摄的多个图像的数据,并通过图像融合技术将它们合并。我们的研究展示了关于扩散介质内物体的明显数据,这些数据仅在重建图像中可见。实验结果表明与该研究实验设计中使用的样本有显著相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/3053f51a3fc9/sensors-25-04977-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/c33bca8967cd/sensors-25-04977-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/cf87a77d30db/sensors-25-04977-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/3053f51a3fc9/sensors-25-04977-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/c33bca8967cd/sensors-25-04977-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/cf87a77d30db/sensors-25-04977-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/12390302/3053f51a3fc9/sensors-25-04977-g004.jpg

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本文引用的文献

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Toward real-time margin assessment in breast-conserving surgery with hyperspectral imaging.利用高光谱成像技术实现保乳手术中的实时切缘评估
Sci Rep. 2025 Mar 20;15(1):9556. doi: 10.1038/s41598-025-94526-9.
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Hyperspectral imaging with machine learning for in vivo skin carcinoma margin assessment: a preliminary study.基于机器学习的高光谱成像技术用于评估体内皮肤癌边界:初步研究。
Phys Eng Sci Med. 2024 Sep;47(3):1141-1152. doi: 10.1007/s13246-024-01435-8. Epub 2024 May 21.
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Margin assessment during breast conserving surgery using diffuse reflectance spectroscopy.
应用漫反射光谱技术评估保乳手术中的切缘。
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Diffuse reflectance spectroscopy for accurate margin assessment in breast-conserving surgeries: importance of an optimal number of fibers.用于保乳手术中准确切缘评估的漫反射光谱法:最佳光纤数量的重要性。
Biomed Opt Express. 2023 Jul 10;14(8):4017-4036. doi: 10.1364/BOE.493179. eCollection 2023 Aug 1.
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Near-Infrared II Hyperspectral Imaging Improves the Accuracy of Pathological Sampling of Multiple Cancer Types.近红外二区高光谱成象提高了多种癌症类型病理取样的准确性。
Lab Invest. 2023 Oct;103(10):100212. doi: 10.1016/j.labinv.2023.100212. Epub 2023 Jul 12.
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Toward Intraoperative Margin Assessment Using a Deep Learning-Based Approach for Automatic Tumor Segmentation in Breast Lumpectomy Ultrasound Images.迈向使用基于深度学习的方法进行术中切缘评估,以实现乳腺肿块切除术超声图像中的肿瘤自动分割。
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Int J Cancer. 2021 Aug 1;149(3):635-645. doi: 10.1002/ijc.33570. Epub 2021 May 4.
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Biomed Opt Express. 2020 Feb 14;11(3):1216-1230. doi: 10.1364/BOE.381358. eCollection 2020 Mar 1.
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