Lin Wei, Lou Lingling, Chu Dawei, Lv Yidong, Tian Liujun, Wang Bin
Department of Pain, Weifang People's Hospital, Weifang, Shandong Province, China.
College of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong Province, China.
Front Pain Res (Lausanne). 2025 Aug 12;6:1544909. doi: 10.3389/fpain.2025.1544909. eCollection 2025.
The review aimed to evaluate the efficacy of pulsed radiofrequency (PRF) in treating chronic pain by analyzing recent literature.
This is a narrative review of relevant articles on the effectiveness of PRF for chronic pain.
Search for papers published between November 2014 and November 2024 in the PubMed database that use PRF to treat chronic pain. We used "Pulsed radiofrequency, PRF, Pulsed RF for Pain, chronic pain, neuropathic pain, cancer pain, and osteoarthritis pain" as search terms. Inclusion criteria are as follows: (1) Patients are clearly diagnosed with chronic pain according to the standards of the International Association for the Study of Pain; (2) Pulsed radiofrequency is used to treat chronic pain; (3) Follow-up assessments are conducted to evaluate the degree of pain relief after PRF treatment; (4) Review articles and articles not related to the treatment of chronic pain are excluded.
Preliminary searches yielded 368 relevant articles. After reviewing the titles and abstracts and evaluating the full texts, we ultimately included 80 articles. These articles cover research on pulsed radiofrequency treatment for various chronic pain conditions, including neuropathic pain, osteoarthritis pain, and cancer pain. The study types are diverse, including randomized controlled trials, cohort studies, and case reports. The publication dates of the articles range from 2014 to 2024, ensuring the timeliness and comprehensiveness of the research findings, which reflect the latest advancements and outcomes in the field of pulsed radiofrequency treatment for chronic pain.
This review did not include studies indexed in databases other than PubMed.
This article reviews the research progress of pulsed radiofrequency technology in the field of chronic pain treatment. By searching and analyzing relevant literature from recent years, it summarizes the research findings on the mechanisms of PRF in treating chronic pain, its clinical applications, efficacy evaluation, and safety, and discusses future research directions. This is helpful for clinical physicians to develop more scientific treatment plans when managing chronic pain patients.
本综述旨在通过分析近期文献评估脉冲射频（PRF）治疗慢性疼痛的疗效。
这是一篇关于PRF治疗慢性疼痛有效性的相关文章的叙述性综述。
在PubMed数据库中检索2014年11月至2024年11月发表的使用PRF治疗慢性疼痛的论文。我们使用“脉冲射频、PRF、用于疼痛的脉冲射频、慢性疼痛、神经性疼痛、癌痛和骨关节炎疼痛”作为检索词。纳入标准如下：（1）根据国际疼痛研究协会的标准，患者被明确诊断为慢性疼痛；（2）使用脉冲射频治疗慢性疼痛；（3）进行随访评估以评估PRF治疗后疼痛缓解程度；（4）排除综述文章和与慢性疼痛治疗无关的文章。
初步检索得到368篇相关文章。在审阅标题和摘要并评估全文后，我们最终纳入了80篇文章。这些文章涵盖了脉冲射频治疗各种慢性疼痛状况的研究，包括神经性疼痛、骨关节炎疼痛和癌痛。研究类型多样，包括随机对照试验、队列研究和病例报告。文章的发表日期从2014年到2024年，确保了研究结果的及时性和全面性，反映了脉冲射频治疗慢性疼痛领域的最新进展和成果。
本综述未包括PubMed以外数据库中索引的研究。
本文综述了脉冲射频技术在慢性疼痛治疗领域的研究进展。通过检索和分析近年来的相关文献，总结了PRF治疗慢性疼痛的机制、临床应用、疗效评估和安全性的研究结果，并讨论了未来的研究方向。这有助于临床医生在管理慢性疼痛患者时制定更科学的治疗方案。
