Hyman Jodi, Slatnik Christa, Ellwood Michelle
Cancer Care Manitoba, CC33 825 Sherbrook Street, Winnipeg, MB R3A 1M5,
Cancer Care Manitoba, 675 McDermot Ave., Winnipeg, MB R3E 0V9,
Can Oncol Nurs J. 2025 Jan 1;35(1):244-263. eCollection 2025 Winter.
Over the past several decades, there has been excellent progress in cervical cancer prevention and early detection. However, there are still many Canadian woman who will be diagnosed with cervical cancer and will require active treatment. Advancements in personalizing treatment options based on specific staging and fertility-sparing preferences have helped decrease morbidities for some while ensuring well-needed aggressive treatment for others. Surgical procedures, for example, offer a variety of options with curative intent, particularly for those with earlier stage disease. Once the cancer has spread beyond the cervix to locally advanced stages 2 and 3, the combination of chemotherapy and radiation tends to be the mainstay treatment option. Finally, as cancer becomes more advanced into later stages 3 and 4 disease, utilizing traditional chemotherapy with the addition of novel drugs, such as monoclonal antibodies and immune check point inhibitors, offers hope where it was once lacking. This article focuses on these varying treatment options and identifies how nurses are in the prime position to help patients improve overall understanding, tolerance, and continuity of their treatment plan.
在过去几十年里,宫颈癌的预防和早期检测取得了显著进展。然而,仍有许多加拿大女性会被诊断出患有宫颈癌并需要积极治疗。根据特定分期和保留生育功能的偏好来个性化治疗方案的进展,在帮助一些人降低发病率的同时,也确保了另一些人能得到急需的积极治疗。例如,手术程序提供了多种具有治愈意图的选择,特别是对于那些处于早期疾病阶段的患者。一旦癌症扩散到宫颈以外,进入局部晚期2期和3期,化疗和放疗相结合往往是主要的治疗选择。最后,随着癌症发展到更晚期的3期和4期疾病,在传统化疗的基础上添加单克隆抗体和免疫检查点抑制剂等新药,为曾经毫无希望的情况带来了希望。本文重点介绍这些不同的治疗选择,并确定护士如何处于帮助患者提高对治疗计划的整体理解、耐受性和治疗连续性的最佳位置。