Recent Advances in Microneedle Technology for Skin Antiaging.

Microneedle (MN) technology is rapidly gaining popularity as a skin treatment option, particularly in the field of antiaging. Driven by an aging population and the increasing desire for aesthetic enhancement, the pursuit of effective solutions for skin aging has become a major focus in medical aesthetics, emphasizing the need for innovative treatments. MN technology offers a compelling alternative for creating microchannels in the skin and stimulating natural healing and regeneration processes. This approach enhances mechanical stimulation, facilitates drug delivery, restores skin vitality, and improves skin elasticity, ultimately leading to significant antiaging effects. In this review, we discuss the principles and structural features of MN technology, highlighting their relevance to the underlying mechanisms of skin aging, including mechanical structural breakdown, barrier dysfunction, and metabolic issues. We further explored the applications of MNs in dermatological treatments and analyzed clinical research to evaluate the efficacy of MN technology in addressing skin aging. Finally, we discuss the future applications and research directions of MN. Despite its considerable potential, MN technology faces several challenges, including the need for standardized treatment protocols, a comprehensive evaluation of long-term effects, and careful consideration of individual patient variations. Overcoming these issues is crucial for the broader clinical application of this promising technology.