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马凡综合征患者选择性玻璃体视网膜手术的适应证及预后

Indications and Outcomes of Select Vitreoretinal Surgery in Patients With Marfan Syndrome.

作者信息

Kiryakoza Lauren C, Sengillo Jesse D, da Cruz Natasha F S, Uhr Joshua H, Townsend Justin, Berrocal Audina M, Sridhar Jayanth, Lam Byron L, Smiddy William E, Flynn Harry W

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Retinal and Ophthalmic Consultants, P.C., Northfield, NJ, USA.

出版信息

J Vitreoretin Dis. 2025 Aug 22:24741264251362883. doi: 10.1177/24741264251362883.

Abstract

To report clinical indications and outcomes of select vitreoretinal surgery in patients with Marfan syndrome. A retrospective consecutive case series of patients with Marfan syndrome undergoing surgery was performed. Data collected included demographics, systemic and ocular history, refraction, and preoperative and postoperative examination findings. Twenty-seven patients (39 eyes) with Marfan syndrome who underwent vitreoretinal surgery were included. Mean age at time of surgery was 37 years, and mean follow-up duration was 4 years. Surgical indications for patients with Marfan syndrome included visually significant crystalline lens subluxation (n = 25 eyes), rhegmatogenous retinal detachment (RRD) (n = 9 eyes), and dislocated intraocular lens implants (n = 5 eyes). Best-corrected visual acuity was 20/40 or better in 21 eyes undergoing surgery for lens subluxation. For patients undergoing surgery for RRD, anatomic reattachment was achieved by last follow-up in 8 eyes (89%). Pars plana lensectomy and vitrectomy for crystalline lens subluxation was the most common vitreoretinal surgery in patients with Marfan syndrome.

摘要

报告马凡综合征患者行特定玻璃体视网膜手术的临床指征及手术结果。对接受手术的马凡综合征患者进行回顾性连续病例系列研究。收集的数据包括人口统计学资料、全身和眼部病史、验光结果以及术前和术后检查结果。纳入27例(39只眼)接受玻璃体视网膜手术的马凡综合征患者。手术时的平均年龄为37岁,平均随访时间为4年。马凡综合征患者的手术指征包括具有明显视力影响的晶状体半脱位(25只眼)、孔源性视网膜脱离(RRD,9只眼)和人工晶状体植入物脱位(5只眼)。21只接受晶状体半脱位手术的眼中,最佳矫正视力达到20/40或更好。对于接受RRD手术的患者,在最后一次随访时,8只眼(89%)实现了解剖复位。晶状体半脱位的扁平部晶状体切除术和玻璃体切除术是马凡综合征患者最常见的玻璃体视网膜手术。

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