Suppr超能文献

活体肝移植中右移植静脉植入下腔静脉的特点。

Peculiarities of implantation of the right graft veins into the inferior vena cava during living donor liver transplantation.

作者信息

Beridze Davit, Mikeladze Lasha, Tomadze Gia, Kordzaia Dimitri, Kashibadze Kakhaber

机构信息

Department of Surgery, New Vision University, Tbilisi 0159, Georgia.

Department of Surgery, Tbilisi State Medical University, Tbilisi 0160, Georgia.

出版信息

World J Transplant. 2025 Sep 18;15(3):102378. doi: 10.5500/wjt.v15.i3.102378.

Abstract

BACKGROUND

Living donor liver transplantation (LDLT) is a crucial alternative to deceased donor transplantation, especially in regions with limited access to cadaveric organs. Right lobe graft implantation into the inferior vena cava (IVC) requires advanced surgical techniques to optimize outcomes and reduce complications.

AIM

To compare two venous anastomosis techniques-direct polytetrafluoroethylene (PTFE) grafting of V5-V8 veins to the IVC triangulation to the right hepatic vein (RHV)-in terms of graft viability and postoperative outcomes.

METHODS

A retrospective analysis was conducted on 96 patients who underwent LDLT with right lobe grafts between 2014 and 2023. Patients were divided into three groups: (1) No venous outflow reconstruction; (2) PTFE graft direct anastomosis to the IVC; and (3) PTFE graft anastomosis using triangulation to the RHV. Perioperative and postoperative outcomes, including bile duct complications, alanine aminotransferase/aspartate aminotransferase levels, and graft perfusion, were compared across groups.

RESULTS

Group 3 (triangulation to RHV) showed significantly improved venous outflow, fewer complications, and faster normalization of liver function tests. Bile duct complications were highest in group 1 (12.8%) and lowest in group 3 (7%). Doppler ultrasonography revealed better graft perfusion in group 3 compared to groups 1 and 2.

CONCLUSION

Triangulation to the RHV improves graft viability, reduces biliary complications, and enhances early postoperative outcomes compared to direct PTFE grafting to the IVC.

摘要

背景

活体肝移植(LDLT)是尸体供肝移植的重要替代方案,尤其是在尸体器官获取受限的地区。右叶移植肝植入下腔静脉(IVC)需要先进的手术技术以优化手术效果并减少并发症。

目的

比较两种静脉吻合技术——将V5 - V8静脉直接与聚四氟乙烯(PTFE)移植片移植至IVC与右肝静脉(RHV)进行三角吻合——在移植肝存活能力和术后效果方面的差异。

方法

对2014年至2023年间接受右叶移植肝LDLT的96例患者进行回顾性分析。患者分为三组:(1)未进行静脉流出道重建;(2)PTFE移植片直接与IVC吻合;(3)采用三角吻合技术将PTFE移植片与RHV吻合。比较各组围手术期和术后的各项指标,包括胆管并发症、丙氨酸氨基转移酶/天冬氨酸氨基转移酶水平以及移植肝灌注情况。

结果

第3组(与RHV进行三角吻合)显示静脉流出道明显改善,并发症更少,肝功能检查恢复正常的速度更快。第1组胆管并发症发生率最高(12.8%),第3组最低(7%)。多普勒超声检查显示,与第1组和第2组相比,第3组移植肝灌注情况更好。

结论

与将PTFE移植片直接移植至IVC相比,与RHV进行三角吻合可提高移植肝的存活能力,减少胆管并发症,并改善术后早期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed78/12038581/6b10fe095e92/102378-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验