Yamada Takeshi, Kawakami Shiori, Taniguchi Norimasa, Nakajima Shunsuke, Hata Tetsuya, Takahashi Akihiko
Cardiovascular Department, Sakurakai Takahashi Hospital, Hyogo, Japan.
Cardiovascular Department, Sakurakai Takahashi Hospital, Hyogo, Japan.
JACC Case Rep. 2025 Aug 27;30(25):104812. doi: 10.1016/j.jaccas.2025.104812.
Despite growing interest in the distal transradial approach (dTRA) for coronary interventions, the risk of hand ischemia remains insufficiently elucidated.
A 72-year-old woman who experienced an out-of-hospital cardiac arrest was successfully resuscitated and diagnosed with acute myocardial infarction. Primary percutaneous coronary intervention was performed via dTRA with intra-aortic balloon pump support. Post-percutaneous coronary intervention, she developed systemic inflammatory response syndrome due to hypoperfusion during resuscitation, requiring high-dose norepinephrine, prolonged intra-aortic balloon pump support, and continuous renal replacement therapy. Ischemic changes gradually developed in her right thumb, which eventually became mummified and required amputation. Arteriography revealed radial artery occlusion and an incomplete superficial palmar arch.
radial artery occlusion following dTRA carries a potential risk of severe hand ischemia, particularly in patients with complex post-percutaneous coronary intervention clinical courses.
TAKE-HOME MESSAGE: This case underscores the importance of vigilant monitoring for ischemic complications associated with dTRA in critically ill patients.
尽管冠状动脉介入治疗的远端桡动脉入路(dTRA)越来越受到关注,但手部缺血的风险仍未得到充分阐明。
一名72岁女性在院外心脏骤停后成功复苏,被诊断为急性心肌梗死。在主动脉内球囊泵支持下通过dTRA进行了初次经皮冠状动脉介入治疗。经皮冠状动脉介入治疗后,由于复苏期间的低灌注,她出现了全身炎症反应综合征,需要大剂量去甲肾上腺素、延长主动脉内球囊泵支持时间以及持续肾脏替代治疗。她的右手拇指逐渐出现缺血性改变,最终变成干尸状并需要截肢。动脉造影显示桡动脉闭塞和掌浅弓不完整。
dTRA后桡动脉闭塞存在严重手部缺血的潜在风险,尤其是在经皮冠状动脉介入治疗后临床过程复杂的患者中。
本病例强调了对重症患者中与dTRA相关的缺血性并发症进行密切监测的重要性。