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神经介入放射学指征与并发症的结果(ONIRIC):择期神经血管内治疗前后的焦虑和抑郁症状、应对策略及生活质量

Outcomes in neurointerventional radiology indications and complications (ONIRIC): Anxiety and depressive symptoms, coping strategies, and quality of life before and after elective neuroendovascular treatment.

作者信息

Riccietti Chiara, Giordano Andrea, Milani Matteo, Canavero Isabella, Boncoraglio Giorgio, Caldiera Valentina, Ganci Giuseppe, Ciceri Elisa

机构信息

Imaging Radiology and Interventional Neuroradiology, Fondazione IRCCS stituto Neurologico Carlo Besta, Milan, Italy.

Neurology, Public Health and Disability Unit, Data Science Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

出版信息

Interv Neuroradiol. 2025 Sep 1:15910199251370630. doi: 10.1177/15910199251370630.

Abstract

BackgroundPatients undergoing elective endovascular treatment for cerebrovascular diseases (CBVD) may face mental health challenges that impact their quality of life (QoL). However, this issue is still rarely addressed in neuro-endovascular research literature and clinical practice. Our single center ongoing project ONIRIC aims to assess anxiety and depressive symptoms, coping, and QoL in CBVD patients treated via endovascular approaches.MethodsWe prospectively enrolled a cohort of patients undergoing elective endovascular procedures over a 6-month period. Patients completed the State-Trait Anxiety Inventory (STAI-S and STAI-T), the Beck Depression Inventory-version II (BDI-II), the Brief Coping Orientation to Problems Experienced Inventory (Brief-Cope), the Euro-QoL 5D-5L, and the World Health Organization Disability Assessment Schedule (WHODAS 2.0) questionnaires at the baseline, and at discharge.ResultsWe included 25 patients (13 females): mean age 60 ± 12.5 years. There was a significant improvement in state anxiety and depressive symptom scores at discharge: the BDI-II scores significantly differed from the ones at baseline ( < .01), as well as the STAI-S scores ( < .01). The coping and QoL scores did not show any changes.ConclusionsTo our knowledge, this research represents one of the few prospective studies examining the psychological and neuropsychological outcomes associated with elective neuro-endovascular treatment of CBDV. Despite the small sample size, our preliminary findings, are consistent with recent literature in related fields, contributing valuable insights to the broader understanding of how these factors influence clinical management. Future directions include the collection of follow-up data, essential for deepening our understanding of this complex and sensitive issue.

摘要

背景

接受择期血管内治疗的脑血管疾病(CBVD)患者可能面临影响其生活质量(QoL)的心理健康挑战。然而,神经血管内研究文献和临床实践中仍很少涉及这个问题。我们单中心正在进行的ONIRIC项目旨在评估通过血管内方法治疗的CBVD患者的焦虑和抑郁症状、应对方式及生活质量。

方法

我们前瞻性地纳入了一组在6个月内接受择期血管内手术的患者。患者在基线和出院时完成了状态-特质焦虑量表(STAI-S和STAI-T)、贝克抑郁量表第二版(BDI-II)、问题应对简表(Brief-Cope)、欧洲五维健康量表5D-5L以及世界卫生组织残疾评定量表(WHODAS 2.0)问卷。

结果

我们纳入了25例患者(13例女性):平均年龄60±12.5岁。出院时状态焦虑和抑郁症状评分有显著改善:BDI-II评分与基线时显著不同(<0.01),STAI-S评分也是如此(<0.01)。应对方式和生活质量评分没有变化。

结论

据我们所知,本研究是少数几项前瞻性研究之一,探讨了与择期神经血管内治疗CBDV相关的心理和神经心理结果。尽管样本量较小,但我们的初步发现与相关领域的最新文献一致,为更全面地理解这些因素如何影响临床管理提供了有价值的见解。未来的方向包括收集随访数据,这对于深化我们对这个复杂而敏感问题的理解至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86d3/12401946/ed3ee620eabf/10.1177_15910199251370630-fig1.jpg

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