Krajewska-Włodarczyk Magdalena, Szeląg Mateusz, Batko Bogdan, Stajszczyk Marcin, Orleański Michał, Podwójcic Krzysztof, Sowiński Jakub, Świderek Maria, Brzosko Marek, Śmiglewska Agata, Kwiatkowska Brygida, Żuber Zbigniew
Clinic of Rheumatology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Department of Analysis and Strategy, Ministry of Health, Warsaw, Poland.
Rheumatol Int. 2025 Sep 2;45(9):212. doi: 10.1007/s00296-025-05966-5.
To estimate the actual incidence and prevalence of psoriatic arthritis (PsA) within a 9-year timeframe in Poland. Patients were defined as having PsA if they had at least two visits more than 90 days apart with ICD-10 codes M07.0, M07.1, M07.2, M07.3, or L40.5 and filled at least one reimbursed prescription for peripheral or axial PsA-specific treatments during this period (including methotrexate, sulfasalazine, ciclosporin, leflunomide, biologics, targeted synthetic drugs, or non-steroidal anti-inflammatory drugs). Data was obtained from the nationwide public payer database, considering gender, age, and region of residence. We observed an incidence rate of 1.1 per 100,000 inhabitants in 2021, compared to 13.2 in 2013. Regarding the age of the first diagnosis, the peak incidence rate decreased, with a more pronounced decline in men. The prevalence of PsA rose from 72.5 individuals per 100,000 in 2013 to 95.5 in 2021, representing approximately 0.1% of the total population in Poland, with a significant predominance of women among patients over 55 years of age. The decline in PsA incidence may be influenced by a strict case definition and improved access to treatment. Higher prevalence in older women suggests potential gender-related differences. The lower peak incidence and younger diagnosis age in men raise questions about whether lower PsA prevalence in older males is linked to higher mortality due to longer disease duration and comorbidities. Further research is needed to clarify these findings.
评估波兰9年时间内银屑病关节炎(PsA)的实际发病率和患病率。若患者至少有两次间隔超过90天的就诊记录,且ICD-10编码为M07.0、M07.1、M07.2、M07.3或L40.5,并在此期间至少开具过一张外周或轴向PsA特异性治疗的报销处方(包括甲氨蝶呤、柳氮磺胺吡啶、环孢素、来氟米特、生物制剂、靶向合成药物或非甾体抗炎药),则定义为患有PsA。数据来自全国公共支付者数据库,同时考虑了性别、年龄和居住地区。我们观察到2021年的发病率为每10万居民1.1例,而2013年为13.2例。关于首次诊断的年龄,发病率峰值下降,男性下降更为明显。PsA的患病率从2013年的每10万人72.5例升至2021年的95.5例,约占波兰总人口的0.1%,55岁以上患者中女性占显著优势。PsA发病率的下降可能受到严格病例定义和治疗可及性改善的影响。老年女性患病率较高表明可能存在性别相关差异。男性较低的发病率峰值和较年轻的诊断年龄引发了一个问题,即老年男性PsA患病率较低是否与因疾病持续时间较长和合并症导致的较高死亡率有关。需要进一步研究来阐明这些发现。