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ZAP-X的解析几何描述、临床节点分布及几何性能及其与伽玛刀的比较

Analytical Geometry Description, Clinical Node Distribution, and Geometric Performance of ZAP-X and Its Comparison With Gamma Knife.

作者信息

Aguilar Borja, Dias Vânia, Pascual Enrique, Trinidad Leonora, Rodrigues Carlos

机构信息

Medical Physics Department, Mercurius Health, Lisbon, PRT.

Radiation Oncology Department, Institute of Advanced Radiosurgery (IRCA), Hospital Viamed Santa Elena, Madrid, ESP.

出版信息

Cureus. 2025 Jul 31;17(7):e89112. doi: 10.7759/cureus.89112. eCollection 2025 Jul.

Abstract

In radiotherapy, it is increasingly common to find specialized devices in different treatment techniques. The ZAP-X is a radiosurgery system which features a sophisticated and complex geometric design that allows to deliver a high dose of precisely targeted radiation while minimizing the radiation effect on the surrounding normal brain tissue. Its combination of yoked gimbals allows a maximum theoretical geometric efficiency of [Formula: see text] steradian solid angle coverage, which means that it is possible to cover 71% of the surface around the patient's head, making the ZAP-X the commercially available radiosurgery system with the largest beam coverage. While irradiation is possible from any angle in the Treatment Delivery System (TDS), collision-free space is limited in the Treatment Planning System (TPS), so the geometric performance that the ZAP-X can achieve in clinical practice is different and smaller than the theoretical geometric efficiency of the system. However, it has greater geometric efficiency (71%) and higher clinical geometric performance (39%) than the Gamma Knife system (31%). A general analytical geometric description of the gyroscopic system is provided, analyzing the movement and the different combinations of positions of its gantries to finally calculate its geometric efficiency, both from a theoretical and clinical point of view, and compare it with the Gamma Knife system.

摘要

在放射治疗中,不同治疗技术中越来越常见到专门的设备。ZAP-X是一种放射外科手术系统,其具有复杂精密的几何设计,能够在将对周围正常脑组织的辐射影响降至最低的同时,提供高剂量的精确靶向辐射。其轭形万向节的组合实现了最大理论几何效率,即[公式:见原文]立体角覆盖,这意味着能够覆盖患者头部周围71%的表面,使ZAP-X成为市售光束覆盖范围最大的放射外科手术系统。虽然在治疗输送系统(TDS)中可以从任何角度进行照射,但在治疗计划系统(TPS)中无碰撞空间有限,因此ZAP-X在临床实践中能够实现的几何性能与系统的理论几何效率不同且较小。然而,它比伽玛刀系统(31%)具有更高的几何效率(71%)和更高的临床几何性能(39%)。本文提供了对该陀螺系统的一般解析几何描述,分析了其机架的运动及其不同位置组合,最终从理论和临床角度计算其几何效率,并与伽玛刀系统进行比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1003/12398670/483a8b08f86c/cureus-0017-00000089112-i01.jpg

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