Mashali Mohamed H, Abdelmohsen Gaser A, Baamer Ahmed S, Elhudairy Mohamed S, Alkhushi Naif A, Bahaidarah Saud A, Abdelsalam Mohamed H, Elakaby Ahmed R, Maghrabi Khadijah A, Azhar Ahmed S, Zaher Zaher F, Al Ata Jameel A, Al-Radi Osman O, Jamjoom Ahmed A, Shihata Mohammad S, Elmahrouk Ahmed F, Dohain Ahmed M, Baamer Faris A, Bekheet Samia A
From the Pediatric Cardiology Division (Mashali, Abdelmohsen, Baamer, Elhudairy, Alkhushi, Bahaidarah, Abdelsalam, Elakaby, Maghrabi, Azhar, Zaher, Al Ata, Dohain, Baamer), Department of Pediatrics, King Abdulaziz University, Jeddah, Saudi Arabia, From the Department of Cardiac Surgery (Al-Radi, Jamjoom, Shihata, Elmahrouk), King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia, From the Department of Pediatrics (Dohain), King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia, From the Department of Cardiology (Abdelsalam), Banaha University, Banha, Egypt, From the Department of Pediatric (Elakaby) Al Azhar University, Cairo, Egypt and from the Division of Pediatric Cardiology (Mashali, Abdelmohsen, Dohain, Bekheet), Department of Pediatrics, Cairo University, Cairo, Egypt.
Saudi Med J. 2025 Sep;46(9):1039-1045. doi: 10.15537/smj.2025.46.9.20250398.
To assess the surgical outcomes of atrioventricular septal defect associated with Tetralogy of Fallot (AVSD)-TOF repair performed at 2 specialized cardiac centers.
From May 2012 to December 2024, 20 patients diagnosed with AVSD-TOF who underwent surgical repair were included.
The median age at the time of surgical repair was 13 months, with a median weight of 8.2 kg (IQR: 6.2-11.5 kg). Biventricular repair was successfully performed in 18 patients (90%), while one and half ventricular repair was required in 2 patients (10%). Before definitive repair, palliative procedures, including bidirectional Glenn shunts, were carried out in 2 patients (10%), and right ventricular outflow tract (RVOT) stenting in another 2 patients (10%). Postoperative complications included a third-degree heart block requiring pacemaker implantation in 10% and chylothorax in 15%. The median duration of chest drains was 10 days. In 40% of patients, reintervention was required, involving catheter-based procedures and redo surgeries for residual lesions. Despite these complexities, overall survival was 90%, with all patients surviving to hospital discharge.
Biventricular repair of AVSD-TOF is feasible and offers favorable early survival. However, the complexity of the condition, frequent reinterventions, and residual lesions highlight the need for individualized surgical/interventional planning and long-term follow-up.