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无人机在运送用于新冠病毒和结核病诊断的生物样本中的应用:一项范围综述

The Use of Unmanned Aerial Vehicles (UAV) on Delivering Biological Samples for COVID-19 and Tuberculosis Diagnosis: A Scoping Review.

作者信息

Rodrigues Olga Maíra Machado, Lopes Izabela Gimenes, de Oliveira Mariah Eduarda Ferreira, Fragoso Mônica Angélica Carreira, de Oliveira Maria Regina Fernandes, Silva Raquel Santos, de Castro E Caldo Lima Glaura Regina, Damazo Amílcar Sabino, Martins Wagner de Jesus

机构信息

Tropical Medicine Center, University of Brasilia, Brasilia, DF, Brazil.

Fiocruz Brasilia, ColLaboratory of Science, Technology, Innovation and Society (CTIS), Brasilia, DF, Brazil.

出版信息

Ther Innov Regul Sci. 2025 Sep 6. doi: 10.1007/s43441-025-00865-0.

Abstract

PURPOSE

To identify and review scientific evidence from experimental studies utilizing unmanned aerial vehicles (UAVs) to transport samples for the diagnosis of COVID-19 and tuberculosis (TB). This exploratory study aims to support the future development of UAVs for transporting biological samples within the Brazilian Unified Health System (SUS).

METHODS

This scoping review defined its eligibility criteria using the PECO acronym, focusing on: Population: biological samples for diagnosing COVID-19 or TB; Exposure: UAV transportation; Comparator: land transportation; Outcomes: Cost, effectiveness, methods for sample preservation, flight parameters (time, altitude, speed, distance), and quality of transported samples. Eligible studies were identified through searches in Medline via PubMed, Scopus, Embase, and Web of Science. Grey literature was explored via Google Scholar.

RESULTS

Of the 2,052 articles initially found, 797 were duplicates, 1,247 were screened by title and abstract and excluded, eight were retrieved (and fully read) of which five met the eligibility criteria and were included in the review. These studies provided diverse evidence regarding cost, operational performance, safety, and sample integrity.

CONCLUSION

The reviewed studies demonstrate promising applications of UAVs in healthcare logistics. However, regulatory and legal frameworks require adaptation to ensure operational safety. Further experimental studies are necessary, particularly involving beyond visual line of sight (BVLOS) operations, to evaluate scalability and potential cost reductions.

摘要

目的

识别并综述利用无人机(UAV)运输样本用于诊断新型冠状病毒肺炎(COVID-19)和结核病(TB)的实验研究中的科学证据。这项探索性研究旨在支持无人机在巴西统一卫生系统(SUS)内运输生物样本的未来发展。

方法

本范围综述使用PECO首字母缩写词确定其纳入标准,重点关注:人群:用于诊断COVID-19或TB的生物样本;暴露:无人机运输;对照:陆地运输;结果:成本、有效性、样本保存方法、飞行参数(时间、高度、速度、距离)以及运输样本的质量。通过在PubMed、Scopus、Embase和Web of Science上检索Medline来识别符合条件的研究。通过谷歌学术搜索探索灰色文献。

结果

在最初找到的2052篇文章中,797篇为重复文章,1247篇通过标题和摘要进行筛选并排除,检索到8篇(并全文阅读),其中5篇符合纳入标准并被纳入综述。这些研究提供了关于成本、运营性能、安全性和样本完整性的多样证据。

结论

综述研究表明无人机在医疗物流中有很有前景的应用。然而,监管和法律框架需要调整以确保操作安全。需要进一步的实验研究,特别是涉及超视距(BVLOS)操作的研究,以评估可扩展性和潜在的成本降低。

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