Macedo Ary Augusto de Castro, Sampaio Danielle Patriota, Silva Natalie Cavalcanti Mareco da, Costa Luigi Carlo da Silva, Andreollo Nelson Adami, Lopes Luiz Roberto
State University of Campinas, Faculty of Medical Sciences, Department of Surgery, Digestive Diseases Surgical Unit - Campinas (SP), Brazil.
Medical Collaborator of Digestive System Disease Diagnostic Center of State University of Campinas (GASTROCENTRO - UNICAMP). Brazil.
Arq Gastroenterol. 2025 Sep 5;62:e24112. doi: 10.1590/S0004-2803.24612024-112. eCollection 2025.
Gastroesophageal reflux disease has a prevalence of 12% in the Brazilian population. Its treatment includes hygienic-dietary changes, use of medications and, in selected cases, surgery with laparos-copic hiatoplasty and Nissen total fundoplication. However, this last treatment modality presents risks of postoperative dysphagia. High Resolution Esophageal Manometry (HREM) has been considered the test of choice for identifying patients who are candidates for surgical treatment at an increased risk of developing dysphagia.
The objective of this study is to carry out a systematic review to evaluate the clinical and manometric factors that predict post-hiatoplasty and Nissen fundoplication dysphagia using HREM.
Having defined the search engine, we used the databases MEDLINE, PUBMED, EBSCOHOST, SCOPUS and EMBASE. 2147 articles were identified. After selection, 11 studies remained.
We concluded that the data from the selected articles are heterogeneous, but there is agreement regarding a higher risk of dysphagia among female patients, patients with dysphagia present in the preoperative period and, about manometric parameters, for patients with dysphagia in the preoperative period, there is a higher incidence of dysphagia resolution for patients with DCI >1000 mmHg.s.cm. In patients with ineffective esophageal motility, it is recommended to perform the Rapid Multiple Swallowing Test to assess the contractile reserve of the eso-phageal body. If there is an increase in contractile strength with this test, it is considered safe to perform a total fundoplication because the incidence of late dysphagia is low in these cases.
胃食管反流病在巴西人群中的患病率为12%。其治疗包括饮食卫生调整、药物使用,在特定情况下还包括腹腔镜裂孔成形术和nissen全胃底折叠术等手术治疗。然而,最后这种治疗方式存在术后吞咽困难的风险。高分辨率食管测压(HREM)被认为是识别手术治疗后发生吞咽困难风险增加的患者的首选检查。
本研究的目的是进行一项系统评价,以评估使用HREM预测裂孔成形术和nissen胃底折叠术后吞咽困难的临床和测压因素。
确定搜索引擎后,我们使用了MEDLINE、PUBMED、EBSCOHOST、SCOPUS和EMBASE等数据库。共识别出2147篇文章。筛选后,剩下11项研究。
我们得出的结论是,所选文章的数据具有异质性,但对于女性患者、术前存在吞咽困难的患者以及测压参数方面,即术前存在吞咽困难的患者中,DCI>1000 mmHg.s.cm的患者吞咽困难缓解发生率较高,在这方面存在共识。对于食管动力无效的患者,建议进行快速多次吞咽试验以评估食管体的收缩储备。如果该试验使收缩强度增加,则认为进行全胃底折叠术是安全的,因为这些病例中晚期吞咽困难的发生率较低。