Meto Aida, Çota Kreshnik, Meto Agron, Bara Silvana, Boschini Luca
Department of Dentistry, Faculty of Dental Sciences, University of Aldent, 1007 Tirana, Albania.
Department of Surgery, Medicine, Dentistry and Morphological Sciences with Interest in Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, 41125 Modena, Italy.
J Clin Med. 2025 Sep 4;14(17):6249. doi: 10.3390/jcm14176249.
: Tooth autotransplantation is a natural tooth replacement method that preserves the periodontal ligament, supporting root development and alveolar bone remodeling. Unlike dental implants, autotransplanted teeth maintain sensory function and adapt better to the mouth. Although once overlooked, new surgical, imaging, and regenerative advances have revived interest in this technique. This narrative review explores the renewed interest in tooth autotransplantation by assessing its benefits, success rates, technological advancements, and role in modern dentistry while evaluating its advantages, limitations, and potential impact on dental care. : A narrative approach was used to provide a comprehensive and descriptive overview of current knowledge on tooth autotransplantation. A literature search was conducted in PubMed, Scopus, and Google Scholar using keywords such as "tooth autotransplantation", "biological tooth replacement", "periodontal ligament", and "dental implants alternative". English-language articles published between 2000 and 2025 were included, covering clinical trials, reviews, and relevant case reports. Selection focused on studies discussing biological mechanisms, clinical techniques, technological advances, and treatment outcomes. : Success rates range from 80% to 95%, with better predictability in younger patients with immature donor teeth. Long-term viability depends on preserving the PDL and performing atraumatic extractions. However, challenges such as root resorption, ankylosis, and appropriate case selection remain significant considerations. Technological advancements, including CBCT, 3D-printed surgical guides, and biomimetic storage media, have improved surgical precision and clinical outcomes. : Tooth autotransplantation is an effective and cost-effective alternative to dental implants, particularly for growing patients or when implants are not suitable. While success depends on surgical skill and proper case selection, improvements in imaging and regenerative techniques have made outcomes more predictable. Future advances in bioengineering, AI-based planning, and regenerative therapies are likely to expand their use in modern dentistry.
牙齿自体移植是一种天然的牙齿替代方法，可保留牙周韧带，支持牙根发育和牙槽骨重塑。与牙种植体不同，自体移植牙保持感觉功能，并且能更好地适应口腔环境。尽管曾经被忽视，但新的外科手术、成像技术和再生技术的进步重新唤起了人们对该技术的兴趣。本叙述性综述通过评估牙齿自体移植的益处、成功率、技术进步及其在现代牙科中的作用，同时评估其优势、局限性以及对牙科护理的潜在影响，探讨了人们对牙齿自体移植重新产生的兴趣。
采用叙述性方法对当前有关牙齿自体移植的知识进行全面且描述性的概述。在PubMed、Scopus和谷歌学术上进行文献检索，使用“牙齿自体移植”“生物性牙齿替代”“牙周韧带”和“牙种植体替代物”等关键词。纳入了2000年至2025年发表的英文文章，涵盖临床试验、综述和相关病例报告。选择重点在于讨论生物学机制、临床技术、技术进步和治疗结果的研究。
成功率在80%至95%之间，在供体牙未成熟的年轻患者中预测性更好。长期存活率取决于保留牙周韧带以及进行无创拔牙。然而，诸如牙根吸收、牙根粘连和合适病例选择等挑战仍是重要的考虑因素。技术进步，包括锥形束计算机断层扫描（CBCT）、3D打印手术导板和仿生储存介质，提高了手术精度和临床效果。
牙齿自体移植是牙种植体的一种有效且经济高效的替代方法，尤其适用于生长发育中的患者或种植体不适用的情况。虽然成功取决于手术技巧和合适的病例选择，但成像和再生技术的进步使结果更具可预测性。生物工程、基于人工智能的规划和再生疗法的未来进展可能会扩大其在现代牙科中的应用。
