成人原发性软脑膜髓母细胞瘤的罕见表现：病例报告
A Rare Presentation of Adult Primary Leptomeningeal Medulloblastoma: Case Report.
作者信息
Hey Grace E, Still Megan E H, Moor Rachel S F, Stanton Amanda, Mitchell Duane A, Orr Brent A, Kresak Jesse L, Yachnis Anthony A, Massini Tara, Ghiaseddin Ashley P
机构信息
University of Florida College of Medicine, Gainesville, Florida, USA.
Lillian S. Wells Department of Neurosurgery, University of Florida College of Medicine, Gainesville, Florida, USA.
出版信息
Case Rep Pathol. 2025 Sep 8;2025:8937543. doi: 10.1155/crip/8937543. eCollection 2025.
Medulloblastomas are tumors of the posterior fossa that have a propensity to develop leptomeningeal metastases along the spinal cord, commonly known as "drop metastases." Medulloblastoma accounts for approximately 1%-2% of all adult brain tumors, and reports of primary leptomeningeal medulloblastoma are extremely limited. Herein, we present a rare case of a 34-year-old woman diagnosed with multifocal primary spinal leptomeningeal medulloblastoma without cranial involvement.
髓母细胞瘤是后颅窝肿瘤，容易沿脊髓发生软脑膜转移，通常称为“播散性转移”。髓母细胞瘤约占所有成人脑肿瘤的1%-2%，而原发性软脑膜髓母细胞瘤的报道极为有限。在此，我们报告一例罕见病例，一名34岁女性被诊断为多灶性原发性脊髓软脑膜髓母细胞瘤，无颅内受累。
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