Mbabazi Irene, Abila Derrick Bary, Muhindo Richard, Sekaggya Christine, Zawedde-Muyanja Stella
Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Uganda Child Cancer Foundation, Kampala, Uganda.
BMJ Public Health. 2025 Sep 14;3(2):e002211. doi: 10.1136/bmjph-2024-002211. eCollection 2025.
Despite efforts to increase HIV testing availability, a substantial number of women living with HIV (WLHIV) remain unaware that they have HIV. We explored the demographic, socioeconomic and clinical characteristics associated with being unaware of HIV status among WLHIV.
Secondary analysis of data from 13 population-based HIV impact assessment surveys. We used weighted χ analysis and log-binomial regression to identify associations between awareness of living with HIV and various factors.
Among 27 983 WLHIV, 7459 (26.6%) were unaware that they were living with HIV. Women at the extremes of age; 15-24 years (adjusted prevalence ratio (aPR): 1.84; 95% CI 1.67 to 2.03, p value <0.01), those >60 years; and those living in rural areas (aPR: 1. 09; 95% CI 1.02 to 1.18, p value 0.02) were more likely to be unaware of that they were living with HIV. Of the 7459 women who were unaware that they were living with HIV, 7071 (94.8%) had long-term HIV infection. Factors associated with long-term HIV infection included: older age 35-44 years (aPR: 1.03; 95% CI 1.02 to 1.08, p value <0.01), 45-59 years (aPR: 1.05; 95% CI 1.01 to 1.09, p value 0.02) and having no sexual partner in the past 12 months (aPR: 1.04; 95% CI 1.00 to 1.09, p value 0.04).
A high proportion of women who were unaware that they were living with HIV had long-term HIV infections. HIV testing interventions should be targeted towards these women to improve early access to HIV treatment.
尽管为增加艾滋病毒检测的可及性做出了努力,但仍有相当数量的感染艾滋病毒的女性(HIV感染女性)不知道自己感染了艾滋病毒。我们探讨了与HIV感染女性未意识到自身艾滋病毒感染状况相关的人口统计学、社会经济和临床特征。
对13项基于人群的艾滋病毒影响评估调查的数据进行二次分析。我们使用加权χ分析和对数二项回归来确定艾滋病毒感染知晓情况与各种因素之间的关联。
在27983名HIV感染女性中,7459名(26.6%)不知道自己感染了艾滋病毒。年龄两端的女性,即15 - 24岁(调整患病率比(aPR):1.84;95%置信区间1.67至2.03,p值<0.01)、60岁以上的女性,以及居住在农村地区的女性(aPR:1.09;95%置信区间1.02至1.18,p值0.02)更有可能不知道自己感染了艾滋病毒。在7459名不知道自己感染了艾滋病毒的女性中,7071名(94.8%)患有长期艾滋病毒感染。与长期艾滋病毒感染相关的因素包括:年龄较大,35 - 44岁(aPR:1.03;95%置信区间1.02至1.08,p值<0.01)、45 - 59岁(aPR:1.05;95%置信区间1.01至1.09,p值0.02),以及在过去12个月内没有性伴侣(aPR:1.04;95%置信区间1.00至1.09,p值0.04)。
很大一部分不知道自己感染了艾滋病毒的女性患有长期艾滋病毒感染。艾滋病毒检测干预措施应针对这些女性,以改善她们尽早获得艾滋病毒治疗的机会。