Raczyńska Wioletta, Radtke-Łysek Alicja, Bohdan Michał, Frankiewicz Anna, Sobiczewski Wojciech, Gruchała Marcin
First Department of Cardiology, Medical University of Gdańsk, 80-952 Gdańsk, Poland.
J Clin Med. 2025 Sep 18;14(18):6590. doi: 10.3390/jcm14186590.
: Although there has been an improvement in the survival rates of patients following heart transplantation, many complications, such as hypertension, continue to develop. The aim of the study was to assess the 24-hour blood pressure profile and hypertension treatment among patients after heart transplantation and comparison to the control group. : A retrospective data analysis included 26 male patients post-heart transplantation and 39 male patients in the control group. During a routine visit, the following data were collected: 24-hour blood pressure monitoring, laboratory tests, and medical history. : Hypertension was diagnosed in 76.9% of heart transplant recipients (HTXr) and in 56.4% of the control group (Cx). During the night-time rest period, diastolic blood pressure values ≥ 70 mmHg were observed in 76.9% of HTXr (vs. 33.33% Cx, = 0.001). The average daytime systolic/diastolic blood pressure did not differ significantly between the groups. It was also observed that the groups differed in circadian blood pressure (ChiML = 15.87, < 0.001), as there were significantly more reverse dippers in HTXr than in the control group (30.8% (8) vs. 10.3% (4)). The same proportions were also noted in HTXr and the control group in terms of isolated nocturnal hypertension. : Heart transplant recipients require a tailored approach to hypertension management, including a variety of medications and appropriate chronotherapy.
尽管心脏移植术后患者的生存率有所提高,但许多并发症,如高血压,仍在不断出现。本研究的目的是评估心脏移植术后患者的24小时血压情况及高血压治疗情况,并与对照组进行比较。
一项回顾性数据分析纳入了26例心脏移植术后男性患者和39例对照组男性患者。在常规就诊期间,收集了以下数据:24小时血压监测、实验室检查和病史。
76.9%的心脏移植受者(HTXr)和56.4%的对照组(Cx)被诊断为高血压。在夜间休息期间,76.9%的HTXr观察到舒张压值≥70 mmHg(对照组为33.33%,P = 0.001)。两组间白天平均收缩压/舒张压无显著差异。还观察到两组在昼夜血压方面存在差异(卡方检验=15.87,P < 0.001),因为HTXr中反勺型血压者显著多于对照组(30.8%(8例)对10.3%(4例))。在单纯夜间高血压方面,HTXr和对照组的比例相同。
心脏移植受者需要一种量身定制的高血压管理方法,包括使用多种药物和适当的时间治疗。