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特应性皮炎和银屑病患者的螨虫感染

Mite Infestation in Patients Suffering from Atopic Dermatitis and Psoriasis.

作者信息

Borzęcka-Sapko Agnieszka, Raszewska-Famielec Magdalena, Sędzikowska Aleksandra, Buczek Alicja, Borzęcki Adam Wilmosz, Bartosik Katarzyna

机构信息

Department of Biology and Parasitology, Chair of Pharmacology and Biology, Faculty of Health Sciences, Medical University of Lublin, Radziwiłłowska 11 St., 20-080 Lublin, Poland.

Med-Laser Non-Public Health Care Centre, 20-406 Lublin, Poland.

出版信息

Pathogens. 2025 Sep 22;14(9):956. doi: 10.3390/pathogens14090956.

DOI:10.3390/pathogens14090956
PMID:41011856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12473025/
Abstract

The role of mites in the pathogenesis of skin diseases still needs updating. The aim of the study was to determine the relationship between sp. infestation and ocular and skin lesions in patients with atopic dermatitis (AD) and psoriasis (PsO). The control group comprised subjects that had not been diagnosed with any inflammatory skin disease. Direct microscopic examination (DME) was applied to analyze eyelashes and skin scraping samples. mites were detected more often in the eyelash samples than in the skin in both the AD (16.7% vs. 6.7%) and PsO (18.5% vs. 7.4%) patients as well as in the control group (25.8% vs. 3%). The mean intensity of infestation was 4.25 in the AD patients, 3.4 in the PsO patients, and 2.8 in the control group. Emollients were used in the treatment by 76.7% of the AD patients and 64.8% of patients with PsO; however, this type of skin care did not significantly increase the risk of skin colonization by . AD and PsO do not seem to facilitate excessive sp. proliferation. Nevertheless, diagnosis of the presence of these mites should be considered in patients with facial skin and ocular lesions that do not respond to the treatment.

摘要

螨虫在皮肤病发病机制中的作用仍需更新。本研究的目的是确定特应性皮炎(AD)和银屑病(PsO)患者中[具体螨虫种类]感染与眼部及皮肤病变之间的关系。对照组包括未被诊断患有任何炎症性皮肤病的受试者。采用直接显微镜检查(DME)分析睫毛和皮肤刮片样本。在AD患者(16.7%对6.7%)、PsO患者(18.5%对7.4%)以及对照组(25.8%对3%)中,睫毛样本中检测到螨虫的频率均高于皮肤样本。AD患者的[具体螨虫种类]感染平均强度为4.25,PsO患者为3.4,对照组为2.8。76.7%的AD患者和64.8%的PsO患者在治疗中使用了润肤剂;然而,这种皮肤护理方式并未显著增加[具体螨虫种类]在皮肤定植的风险。AD和PsO似乎并未促进[具体螨虫种类]过度增殖。尽管如此,对于面部皮肤和眼部病变治疗无反应的患者,应考虑诊断是否存在这些螨虫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/98892caf5749/pathogens-14-00956-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/4d64a2604c9e/pathogens-14-00956-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/ce11a7a24ca3/pathogens-14-00956-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/ab9ab8eddd5b/pathogens-14-00956-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/98892caf5749/pathogens-14-00956-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/4d64a2604c9e/pathogens-14-00956-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/ce11a7a24ca3/pathogens-14-00956-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/ab9ab8eddd5b/pathogens-14-00956-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f120/12473025/98892caf5749/pathogens-14-00956-g004.jpg