Dalla Serra Giulia, Skelly Cliona, Amorós Carafí Olga
Department of Diagnostic Imaging, School of Veterinary Medicine, UCD Veterinary Hospital, University College Dublin, Belfield, Dublin 4, D04 W6F6 Dublin, Ireland.
Vet CT Specialists Ltd., Hauser Forum, 21 JJ Thomson Ave, Cambridge CB3 0FA, UK.
Vet Sci. 2025 Aug 26;12(9):813. doi: 10.3390/vetsci12090813.
Metaphyseal osteopathy (MO) is a rare systemic disease primarily affecting young large-breed dogs. Diagnosis of MO is usually based on a combination of signalment, presenting clinical signs, and imaging findings. While radiographic features of MO are well documented, reports describing Computed Tomography (CT) findings are limited. Clinical records of a veterinary teaching hospital were searched for dogs with a presumed diagnosis of MO that underwent CT imaging. CT and available radiographic studies were retrospectively reviewed. Four dogs met the inclusion criteria. All presented with pyrexia, often associated with other clinical signs. CT lesions were bilateral and symmetric in all cases, characterised by an irregular metaphyseal band of lysis parallel to the physis with associated signs of bone sclerosis. Multiple long bones were affected, and mandibular involvement was suspected in two cases. Comparison with a radiographic study was available in two cases, and follow-up CT imaging was performed in one. Although radiographs remain the primary diagnostic tool for MO, understanding the CT features of the disease is valuable and may contribute to prompt diagnosis, particularly when evaluating young dogs with pyrexia and non-specific clinical signs.
干骺端骨病(MO)是一种罕见的全身性疾病,主要影响大型幼犬。MO的诊断通常基于品种特征、临床表现和影像学检查结果。虽然MO的X线特征已有充分记录,但关于计算机断层扫描(CT)表现的报道有限。检索一家兽医教学医院的临床记录,寻找疑似患有MO且接受CT检查的犬只。对CT和现有的X线研究进行回顾性分析。四只犬符合纳入标准。所有犬均有发热,常伴有其他临床症状。所有病例的CT病变均为双侧对称,表现为与生长板平行的不规则干骺端溶骨带,并伴有骨质硬化迹象。多根长骨受累,两例怀疑下颌骨受累。两例可与X线检查结果进行对比,一例进行了CT随访检查。虽然X线片仍是MO的主要诊断工具,但了解该疾病的CT特征很有价值,可能有助于早期诊断,尤其是在评估发热且有非特异性临床症状的幼犬时。