Naqvi Jaffer, Wall Michael, Chung Sophia M, Thurtell Matthew, Linton Edward, Rodriguez-Barrath Adriana, Kardon Randy
Department of Ophthalmology and Visual Science, Neuro-Ophthalmology Division, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Department of Veterans Affairs, Iowa City Health Care System (Surgery Division) and the Iowa City Center for the Prevention and Treatment of Visual Loss, Iowa City, IA, USA.
Eye Brain. 2025 Oct 1;17:125-136. doi: 10.2147/EB.S492845. eCollection 2025.
Idiopathic Intracranial Hypertension (IIH) is characterized by elevated intracranial pressure in the absence of secondary causes. The treatment of IIH entails a combination of lifestyle modifications, medical therapy, and surgical intervention. This article aims to evaluate the role of acetazolamide in the treatment of IIH and identify its mechanism of action, efficacy, and side effect profile. This article also aims to discuss acetazolamide's role in conjunction with other treatment modalities.